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- Violeta Fernández-Santana, Félix Cardoso, +16 authors Vicente Vérez-Bencomo
- Infection and immunity
- 2004

Polysaccharide-protein conjugates as vaccines have proven to be very effective in preventing Haemophilus influenzae type b infections in industrialized countries. However, cost-effective technologies need to be developed for increasing the availability of anti-H. influenzae type b vaccines in countries from the developing world. Consequently, vaccine… (More)

- Ricardo Soto, Broderick Crawford, +5 authors Eduardo Olguín
- Natural Computing
- 2016

The set covering problem is a classical optimization benchmark that finds application in several real-world domains, particularly in line balancing production, crew scheduling, and service installation. The problem consists in finding a subset of columns in a zero-one matrix such that they cover all the rows of the matrix at a minimum cost. In this paper,… (More)

- Ricardo Soto, Broderick Crawford, Ignacio Figueroa, Rodrigo Olivares, Eduardo Olguín
- 2016 11th Iberian Conference on Information…
- 2016

The Set Covering Problem is a classical problem in combinatorial optimization that belongs to the Karp's 21 NP-hard problems, with many practical applications. In this paper, an approach based on Black Hole Algorithm is proposed to solve this problem. The black hole algorithm is a metaheuristic that is inspired by nature, especially by the black hole… (More)

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