Ignacio Figueroa

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Polysaccharide-protein conjugates as vaccines have proven to be very effective in preventing Haemophilus influenzae type b infections in industrialized countries. However, cost-effective technologies need to be developed for increasing the availability of anti-H. influenzae type b vaccines in countries from the developing world. Consequently, vaccine(More)
The set covering problem is a classical optimization benchmark that finds application in several real-world domains, particularly in line balancing production, crew scheduling, and service installation. The problem consists in finding a subset of columns in a zero-one matrix such that they cover all the rows of the matrix at a minimum cost. In this paper,(More)
The Set Covering Problem is a classical problem in combinatorial optimization that belongs to the Karp's 21 NP-hard problems, with many practical applications. In this paper, an approach based on Black Hole Algorithm is proposed to solve this problem. The black hole algorithm is a metaheuristic that is inspired by nature, especially by the black hole(More)
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