Idris Ajayi Oyemitan

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This study investigated the hypnotic, anti-convulsant and anxiolytic effects of 1-nitro-2-phenylethane (BPNE) obtained from the oil of Dennettia tripetala G. Baker (Annonaceae) and established its mechanism of action. The essential oil (EO) from the leaf, fruit and seed was obtained by hydrodistillation, followed by isolation of BPNE purified to 99.2% by(More)
ETHNOPHARMACOLOGICAL RELEVANCE Piper guineense Schum & Thonn (Piperaceae) is a medicinal plant used in the Southern States of Nigeria to treat fever, mental disorders and febrile convulsions. AIMS OF THE STUDY This study aims at determining the chemical composition and the central nervous system (CNS) activities of the essential oil obtained from the(More)
In this study we evaluated the analgesic and anti-inflammatory activities of the essential oil (EO) of the fruits of Dennettia tripetala in rodents. The plant is a tropical African plant and the fruits are commonly eaten as spices and consumed as a stimulant, and its various parts are used in the treatment of fever, cough and as anti-emetics.The analgesic(More)
We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver(More)
  • Lateef Abiola Akinpelu, Theophilus Adekunle Adegbuyi, +5 authors Gbola Olayiwola
  • 2017
Objective: Vigna unguiculata ssp. dekindtiana (L.) Walp is used in traditional practice to treat depression-like disorders in some communities of Southwest Nigeria. This study investigated the antidepressant-like effects of the aqueous fraction of the dried aerial parts of V. unguiculata ssp. dekindtiana (AFVU). Methodology: AFVU was evaluated for(More)
OBJECTIVE Determination of the active fraction and compounds of the dichloromethanol extract of Schinus molle seeds and evaluation of their biological effects. MATERIALS AND METHODS Dried seeds of Schinus molle were sequentially extracted in hexane, acetyl acetate and dichloromethane. The dichloromethane extract was separated into two fractions (1 and 2)(More)
Alternanthera brasiliana is a medicinal plant used in the folkloric treatment of malaria, pains, infections and diabetes in South-western states of Nigeria. Recent reports indicate some central activities for the plant. This study evaluated ethanolic leaf extract of the plant for novelty-induced behaviour, anxiety, sedation and convulsion in mice. Dried(More)
BACKGROUND Curcuma longa (turmeric) is commonly used as spice and also used to treat fever, cough and febrile convulsions in Nigeria. This study determined the chemical composition of the essential oil of C. longa and evaluated its neuropharmacological activity in mice. METHODS Essential oil of C. longa (EOCL) fresh rhizome was obtained by(More)
Echinacea is used ethnomedicinally for the treatment of various diseases such as cough, respiratory infections, and bronchitis among other uses in Eastern Cape region of South Africa. This study evaluated the volatile components of the essential oil of the plant, its toxicity, anti-inflammatory and analgesic activities in rodents. Dried leaf and root of the(More)
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