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Ecogenomic survey of plant viruses infecting Tobacco by Next generation sequencing
TLDR
This study describes the discovery of a consortium of plant viruses infecting Tobacco that are broadly distributed in Anhui province of China and demonstrates the effectiveness of NGS in identifying plant viruses without a prior knowledge of the virus and the genetic diversity that enhanced mixed infection.
Understanding the immune system architecture and transcriptome responses to southern rice black-streaked dwarf virus in Sogatella furcifera
TLDR
It is revealed that feeding on SRBSDV-infected rice plants has a significant impact on gene expression, regardless of viral titers in insects, and the RNAi pathway was the major antiviral response to increasing viral titer among diverse immune responses.
A Mechanism-Based Targeted Screen To Identify Epstein-Barr Virus-Directed Antiviral Agents
TLDR
A high-throughput screening assay is developed that is able to measure a key step that is essential for successful completion of EBV’s lytic cascade and may be used as a platform to identify both antiherpesviral and anticancer drugs.
Complete genome sequence of a novel velarivirus infecting areca palm in China
The complete genome of a novel virus, provisionally named areca palm velarivirus 1 (APV1), was identified in areca palm exhibiting leaf yellowing symptoms in Hainan province, China. The genome of
Genome sequence of a rice pest, the white-backed planthopper (Sogatella furcifera)
TLDR
The first assembled and annotated whole genome sequence and transcriptome of S. furcifera is reported, which will be a valuable resource for ecological and virus–host interaction studies of this pest.
Complete genome sequence of tobacco virus 1, a closterovirus from Nicotiana tabacum
TLDR
This study is the first report of the complete genome sequence of a closterovirus identified in tobacco, containing nine open reading frames (ORFs) that potentially encode proteins with putative functions in virion assembly, cell-to-cell movement and suppression of RNA silencing.
Identification and characterization of microRNAs in the white‐backed planthopper, Sogatella furcifera
TLDR
Comparison with miRNAs from 26 insect species and five other species in miRBase showed that more than half of the conserved miRNA families are highly conserved in Hexapoda, while other mi RNAs are only conservedin non‐dipterans.
SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway
TLDR
In a pared-down system, the influence of ORF3a, an essential SARS-CoV-2 protein, is investigated on the inflammatory machinery and it is found that it activates NLRP3, the most prominent inflammasome by causing potassium loss across the cell membrane.
A heterochromatin inducing protein differentially recognizes self versus foreign genomes
TLDR
In situ footprint mapping on both viral and host genomes in physically separated B-lymphocytes bearing latent or replicative/active EBV genomes learned that SZF1 recognizes the host genome through a repeat sequence-bearing motif near centromeres, but does not use this motif to recognize the EBV genome.
Nascent Transcriptomics Reveal Cellular Prolytic Factors Upregulated Upstream of the Latent-to-Lytic Switch Protein of Epstein-Barr Virus
TLDR
Investigation into the partially permissive phenotype of the herpesvirus Epstein-Barr virus (EBV) indicates that upon exposure to lytic triggers, certain cellular genes are transcriptionally upregulated, while viral latency genes are downregulated ahead of expression of the viral latent-to-lytic switch protein.
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