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- Florence Vollenweider, K. L. Leenders, Ibrahim Haruna Oye, Daniel Hell, Jules Angst
- European neuropsychopharmacology : the journal of…
- 1997
Until recently, racemic ketamine (S-ketamine/R-ketamine = 50:50) has been used to study NMDA receptor hypofunction in relation to pathophysiological models of schizophrenia. Ketamine given to normal… (More)
- Ibrahim Haruna Oye, Ole Paulsen, A R Maurset
- The Journal of pharmacology and experimental…
- 1992
The chiral forms of ketamine were applied as probes for N-methyl-D-aspartate receptor-mediated neurotransmission in humans. Both enantiomers, in clinically relevant concentrations, displaced… (More)
- Frode Willoch, G. Rosen, +5 authors P. Bartenstein
- Annals of neurology
- 2000
Pain and other phantom limb (PL) sensations have been proposed to be generated in the brain and to be reflected in activation of specific neural circuits. To test this hypothesis, hypnosis was used… (More)
- Tor Erik Rabben, Per Skjelbred, Ibrahim Haruna Oye
- The Journal of pharmacology and experimental…
- 1999
We examined the role of N-methyl-D-aspartate (NMDA) receptors in chronic (pathological) pain in humans by using the NMDA receptor antagonist ketamine as a probe. Thirty patients with neuropathic pain… (More)
- Franz X. Vollenweider, Peter Vontobel, Ibrahim Haruna Oye, Daniel Hell, K. L. Leenders
- Journal of psychiatric research
- 2000
Administration of the N-methyl-D-aspartate (NMDA) antagonist S-ketamine in normals produces a psychosis-like syndrome including several positive and negative symptoms of schizophrenic disorders… (More)
- Olav Hustveit, A R Maurset, Ibrahim Haruna Oye
- Pharmacology & toxicology
- 1995
In order to elucidate the mechanisms of action of ketamine, we have investigated the binding of the chiral forms of ketamine to opioid (mu, delta and kappa), phencyclidine, sigma and muscarinic… (More)
We examined the analgesic effect of racemic ketamine and its 2 enantiomers in 16 female patients (age: 20-29 years) suffering acute pain after oral surgery and in 7 female patients (age: 42-79 years)… (More)
Malaria is a disease associated with high morbidity and mortality especially among children and other high risk groups. Certain ABO blood group is thought to be protective of severe malaria.… (More)
- PÃ¥l Klepstad, A R Maurset, Erik Moberg, Ibrahim Haruna Oye
- European journal of pharmacology
- 1990
Both chiral forms of ketamine caused analgesia when administered in subanesthetic doses to human volunteers suffering acute, experimentally induced ischemic pain. S-Ketamine was 4 times more potent… (More)
- Paal Hartvig, Johann Valtysson, +7 authors Giorgia Antoni
- Clinical pharmacology and therapeutics
- 1995
Plasma concentrations, maximum regional brain concentrations, and specific regional binding in the brain after administration of 0, 0.1, and 0.2 mg/kg doses of (S)-ketamine were measured in a… (More)