Ibrahim Erkutlu

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BACKGROUND Peripheral nerve damage that requires surgical repair does not result in complete recovery because of collagen scar formation, ischemia, free oxygen radical damage, and other factors. To date, the best treatment method has not yet been determined. In this study, we designed an experimental peripheral nerve injury model, and researched the(More)
Lesions of the fourth ventricle represent a challenge to neurosurgeons because of severe deficits that occur following injury to the delicate structures in the ventricle wall and floor. The conventional approach to the fourth ventricle is by splitting the vermis on the suboccipital surface of the cerebellum. In the last 9 years, a series of 21 patients in(More)
Adenosine has been shown to play a significant role as a modulator of neuronal activity in convulsive disorders, acting as an endogenous anticonvulsant agent. Any change in adenosine deaminase (ADA) levels will reflect to adenosine levels. In the present study, we have investigated the effect of glutathione on brain tissue ADA levels due to seizures induced(More)
Epilepsy can be described as a group of neurological disorders, characterized by recurrent episodes of convulsive seizures, loss of consciousness, sensory disturbances, abnormal behavior, or all of these. Altered glutathione metabolism in association with increased oxidative stress has been implicated in the pathogenesis of many diseases such as seizures.(More)
BACKGROUND Although small meningomyeloceles may be amenable to direct closure by undermining of the surrounding skin, the closure of large meningomyelocele defects is a challenging reconstructive problem. PURPOSE Here, we present a new surgical procedure for the closure of large meningomyelocele defects. MATERIAL AND METHODS In this procedure, after(More)
Background. We report an assessment of the efficiacy of a triple layer graft composed of fascia lata and vascularized pericranium for anterior skull base reconstruction. This technique is based on the concept that vascularized tissue over a free flap may promote vascularization and rapid wound healing. Method. A large fascial graft is prepared from the(More)
Single seizure and epilepsy is one of the most commonly encountered neurologic disorders in elderly individuals, arising as a result of complex and often multiple acquired underlying pathologies. Adenosine, acting at A1 receptors, exhibits anticonvulsant effects in experimental epilepsy and inhibits progression to status epilepticus. Adenosine deaminase is(More)
BACKGROUND Myoclonic movements are common problems during induction of anesthesia with etomidate. The aim of this study was to compare the effect of pretreatment with dexmedetomidine (0.5 microg/kg) and thiopental (1 mg/kg) on the incidence of etomidate-induced myoclonus and postoperative pain. MATERIALS AND METHODS A prospective double-blind study was(More)
In this paper, we report a rare case of a 29-year-old boy who presented with papillary meningioma originating from the posterior fossa meninges. After a long, disease-free period, however, spinal drop metastases occurred 32 months after resection of the primary tumor. The primary and metastatic lesions had a similar histological appearance, meaning that(More)
Glioblastoma multiforme (GBM) is the most common and the most aggressive primary malignant tumor of the brain. Prognostic factors in GBM can be sorted as age, tumor localization, tumor diameter, symptom period and type, the extent of surgery, postoperative tumor volume, and adjuvant radiotherapy and/or chemotherapy status. Besides the interactions between(More)