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A frequency plot of all 3000 J 1 values associated with partitions found by applying HCM to the Lena image when the degenerate c = 1 v alue is left out. 19 ii Abstract This paper describes a genetically guided approach to optimizing the hard J 1 and fuzzy J m c-means functionals used in cluster analysis. Our experiments show that a genetic algorithm(More)
Organizing and annotating biomedical data in structured ways has gained much interest and focus in the last 30 years. Driven by decreases in digital storage costs and advances in genetics sequencing, imaging, electronic data collection, and microarray technologies, data is being collected at an ever increasing rate. The need to store and exchange data in(More)
The aggregation of imaging, clinical, and behavioral data from multiple independent institutions and researchers presents both a great opportunity for biomedical research as well as a formidable challenge. Many research groups have well-established data collection and analysis procedures, as well as data and metadata format requirements that are particular(More)
Managing vast datasets collected throughout multiple clinical imaging communities has become critical with the ever increasing and diverse nature of datasets. Development of data management infrastructure is further complicated by technical and experimental advances that drive modifications to existing protocols and acquisition of new types of research data(More)
Investigators perform multi-site functional magnetic resonance imaging studies to increase statistical power, to enhance generalizability, and to improve the likelihood of sampling relevant subgroups. Yet undesired site variation in imaging methods could off-set these potential advantages. We used variance components analysis to investigate sources of(More)
Ever increasing size of the biomedical literature makes tapping into implicit knowledge in scientific literature a necessity for knowledge discovery. In this paper, a semantic parser for recognizing semantic roles and named entities in individual sentences of schizophrenia related scientific abstracts is described. The named entity recognizer, CRFNER,(More)
A method for chemical process fault diagnosis using semiquantitative model generated behavior envelopes is described in this paper. The method generates a sequence of rules for each fault class, with any rule in a sequence valid within the bounds of its time interval. This can be viewed as a qualitative description of the trend of numerical sensor(More)
Arterial spin labeling (ASL) is a magnetic resonance imaging technique that provides a non-invasive and quantitative measure of cerebral blood flow (CBF). After more than a decade of active research, ASL is now emerging as a robust and reliable CBF measurement technique with increased availability and ease of use. There is a growing number of research and(More)