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IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells

• Jill R Johnson, Michiyoshi Nishioka, +7 authors Qutayba A. Hamid
• Respiratory research
• 2013

BACKGROUND Allergic asthma is characterized by airway inflammation in response to antigen exposure, leading to airway remodeling and lung dysfunction. Epithelial-mesenchymal transition (EMT) may play… (More)

5-Oxoprolinase deficiency: report of the first human OPLAH mutation.

• Ibrahim Almaghlouth, J Y Mohamed, Mohammed Hussein Al-Amoudi, Lujane Y Al-Ahaidib, Ahmad Al-Odaib, F. S. Alkuraya
• Clinical genetics
• 2012

Gamma-glutamyl cycle is a six-enzyme cycle that represents the primary pathway for glutathione synthesis and degradation. 5-Oxoprolinase deficiency is an extremely rare disorder of the gamma-glutamyl… (More)

IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis.

• Eric Gracey, Zoya Qaiyum, +8 authors Robert D. Inman
• Annals of the rheumatic diseases
• 2016

OBJECTIVE Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown origin in which interleukin (IL) 17 has been genetically and therapeutically recognised as a key player.… (More)

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