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Light microscopy studies have demonstrated heightened ICAM-1 and VCAM-1 expression in renal allograft rejection in experimental animals and in humans, and administration of ICAM-1 blocking antibodies… (More)
ConclusionsThe infiltration and activation of leukocytes within the glomerulus and interstitium play a key role in the initiation and progression of glomerulonephritis. The recent characterization of… (More)
The fundamental role of cell-mediated immunity in inflammatory disease of the kidney has been established for some time. This review focusses on the recent advances in our understanding of the role… (More)
Summary: Understanding the complex mechanisms involved in the induction and progression of glomerulonephritis requires a detailed analysis of the disease at the molecular level. This has become… (More)