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OBJECTIVE To determine whether screening and treating women for chlamydial infection reduces the incidence of pelvic inflammatory disease over the subsequent 12 months. DESIGN Randomised controlled trial. SETTING Common rooms, lecture theatres, and student bars at universities and further education colleges in London. PARTICIPANTS 2529 sexually active(More)
OBJECTIVE The objective of this study was to characterize the resurgence of infectious syphilis in the United Kingdom between 1997 and 2003. STUDY The authors conducted a retrospective analysis of routine surveillance data from genitourinary medicine clinics and data collected through enhanced surveillance. RESULTS Between 1997 and 2002, diagnoses of(More)
BACKGROUND The role of Mycoplasma genitalium in pelvic inflammatory disease is unclear. We conducted a cohort study to determine the prevalence and predictors of M. genitalium infection in female students, to explore its role in pelvic inflammatory disease and to estimate its annual incidence and persistence rate. METHODS Two thousand three hundred(More)
OBJECTIVES To investigate the drivers behind the epidemic expansion of lymphogranuloma venereum (LGV) cases in late 2009 to help inform infection control. METHODS An epidemic curve of all LGV diagnoses between 2003 and mid-2012 was plotted and divided into the initial detection period, and endemic, growth and hyperendemic phases. Detailed clinical and(More)
OBJECTIVE To describe the contribution of primary care to the diagnosis and management of sexually transmitted infections in the United Kingdom, 1990-2000, in the context of increasing incidence of infections in genitourinary medicine clinics. DESIGN Population based study. SETTING UK primary care. PARTICIPANTS Patients registered in the UK general(More)
This paper reviews national routine data pertaining to sexual ill health among teenagers in England and Wales; birth and termination statistics from the Office for National Statistics; and reports from sexually transmitted disease (STD) clinics. There were 86,174 conceptions among females under age 20 in 1996, of which 30,296 were terminated and 55,878 led(More)
The aim of this article is to describe trends in infectious syphilis in the UK, and specifically the epidemiology of the London syphilis outbreak, the largest in the UK to date. Analysis of routine surveillance data from genitourinary medicine (GUM) clinics was performed as well as data collection through enhanced surveillance systems. There have been(More)
OBJECTIVE To investigate factors associated with variations in diagnoses of primary, secondary and early latent syphilis in England and Wales. METHODS Data were derived from two sources: diagnoses made in genitourinary medicine clinics reported on form KC60, and information collected through National Enhanced Syphilis Surveillance (NESS). Multinomial(More)
Introduction It is a decade since this bleak view of pelvic inflammatory disease (PID) management in the United Kingdom appeared in the BMJ. Since then a theme to emerge in sexually transmitted disease (STD) research has been increased awareness of genital chlamydial infection, which causes a substantial proportion of PID cases. In the United Kingdom, this(More)