• Publications
  • Influence
Genetic basis for personalized medicine in asthma
There is heterogeneity in patient responses to current asthma medications. Significant progress has been made identifying genetic polymorphisms that influence the efficacy and potential for adverseExpand
  • 40
  • 1
  • PDF
Genome-Wide Association Study Identifies Five New Loci Associated With Lung Function
Emmanouela Repapi, Ian Sayers, Louise V Wain, Paul R Burton, Toby Johnson, Ma‟en Obeidat, Jing Hua Zhao, Adaikalavan Ramasamy, Guangju Zhai, Veronique Vitart, Jennifer E Huffman, Wilmar Igl, EvaExpand
  • 23
  • 1
  • PDF
Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways
BackgroundGenetic studies of human lung function and Chronic Obstructive Pulmonary Disease have identified a highly significant and reproducible signal on 4q24. It remains unclear which of the twoExpand
  • 9
  • PDF
Chapter 28 Asthma
Abstract Asthma is a common respiratory disease with a complex etiology involving a combination of genetic and environmental components. Current asthma management involves a step-up andExpand
  • 3
A process for the production of sheet-like structures
A process for producing a unitary sheet-like structure which is built up of several superimposed layers of plastic material, wherein the plastic material is in layers deposited on an extended workExpand
Urokinase plasminogen activation receptor (uPAR) levels correlate with bronchial epithelial barrier integrity
Rationale: The urokinase plasminogen activation receptor (uPAR) is a membrane bound receptor cleaved at its glycosylphosphatidylinisotol (GPI) anchor to form a full length soluble cleaved formExpand