Ian R. Swan

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Audiological and vestibular tests were administered conjointly in a neurological or general ORL clinic to exclude cerebellopontine angle (CPA) tumours. This study aimed to assess the efficiency of various tests in achieving that exclusion with the minimum of unnecessary investigations. All patients received the full battery of auditory brainstem responses,(More)
Introduction THERE are many occasions when a clinician may wish to 1 test the hearing of a patient to confirm that an impairment is present. There are several ways that this might be done but perhaps the easiest and most relevant is to use free-field voice testing. Voice testing of hearing was the standard method of assessing a person's ability to hear(More)
We have examined the incidence of Harvey ras mutations in human squamous cell carcinomas (SCC) of the upper aerodigestive tract using the polymerase chain reaction (PCR) followed by direct sequencing. No mutations were detected at codons 12, 13, 59 or 61 of this gene in any of six papillomas, five erythroplakias, 56 squamous cell carcinomas, and 16 SCC cell(More)
Seventy-four patients previously treated in our department for germ cell tumour of the testis underwent a series of tests to determine the frequency of long-term therapeutic complications. All had received cisplatin-based chemotherapy as part of their treatment. There was a significant deterioration in renal function throughout the group. Eighteen (24%) had(More)
Clinical tests of hearing are regularly used in adults but their role, now that pure-tone audiometry is almost universally available, has not been evaluated by modern methods of analysis including sensitivity and specificity. Free-field voice testing was carried out in 101 patients and the Rinne tuning-fork test in a different group of 127 patients prior to(More)
Anesthetics such as isoflurane are commonly used to sedate experimental animals during the induction of stroke. Since these agents are known to modulate synaptic excitability, inflammation and blood flow, they could hinder the development and discovery of new neuroprotection therapies. To address this issue, we developed a protocol for inducing(More)
The Bing test is based on the principle that occlusion of the external auditory meatus improves the perception of bone-conducted sounds unless there is a conductive hearing impairment. However, its sensitivity and specificity have not been reported. Tuning-fork and audiometric Bing tests were carried out on 126 patients with otological symptoms prior to any(More)
When assessing hearing by free-field voice testing, it is essential to mask the non-test ear. An appropriate method of masking must be chosen to suit the stimulus used. This study demonstrates that tragal rubbing is an effective means of masking a whispered or conversational voice, but a Bárány noise-box is required to mask a loud voice. However, a Bárány(More)