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Environmental mycobacteria pose a significant health burden. Non-tuberculous mycobacteria infections have been traced to water treatment networks, where mycobacterial biofilms are ubiquitous. Filters that remove potential pathogens have significant medical applications. The purpose of this study is to demonstrate that an antibacterial silver nanoparticle(More)
The construction and long-term maintenance of three-dimensional in vitro bone marrow models is of great interest but still quite challenging. Here we describe the use of a multi-compartment hollow-fiber membrane based three-dimensional perfusion bioreactor for long-term culture of whole human bone marrow mononuclear cells. We also investigated bioreactors(More)
Non-tuberculous mycobacteria are a threat to human health, gaining entry to the body through contaminated water systems, where they form persistent biofilms despite extensive attempts at disinfection. Silver is a natural antibacterial agent and in nanoparticle form activity is increased by a high surface area. Silver nanoparticles (AgNPs) have been used as(More)
This study examined the relationship between sintering and phase transformation behaviour in hydroxyapatite (HA). Pellets and replicated foams were sintered at five different temperatures ranging from 1350 degrees C to 1550 degrees C. Hydroxyapatite remained as the major phase in all the samples studied. In the pellets, sintering took place prior to the(More)
Two computational intelligence approaches, a fuzzy logic algorithm and a neural network (NN) algorithm, for grain boundary detection in images of superalloy steel microstructure during sintering are presented in this paper. The images are obtained from an optical microscope and are quite noisy, which adversely affects the performance of common image(More)
The development of functional engineered tissue constructs depends on high cell densities and appropriate vascularization. In this study we implemented a four-compartment three-dimensional perfusion bioreactor culture model for studying the effects of medium perfusion on endothelial, hepatic, and hematopoietic cell populations of primary human fetal liver(More)
A neural network approach is presented for the estimation of shrinkage during a hot isostatic pressing (HIP) process of nickel-based superalloys for near net-shape manufacture. For the HIP process, the change in shape must be estimated accurately; otherwise, the ®nished piece will need excessive machining and expensive nickel-based alloy powder will be(More)
Quantitative image analysis was used to study the effect of the powder forming method on the population of pull-out flaws for polished surfaces of dense alumina ceramics. By comparing the area fractions, the size distributions and the extreme values of the pull-out areas it was concluded that slip casting with dispersed slips resulted in significantly fewer(More)
This study used quantitative image analysis to examine the effect of powder forming method on a population of dense heterogeneities that could be imaged in partially sintered alumina using optical microscopy. Powder pressing resulted in a higher area fraction of dense heterogeneities than slip casting. Extreme value analysis was used to predict the size of(More)
Aqueous zinc oxide (ZnO) suspensions were prepared using a two-step preparation method in which an aggregated nanocrystalline ZnO powder was dispersed in water using a polyelectrolyte. The fluid showed anomalously high thermal conductivity when compared with the Maxwell and Hamilton-Crosser predictions. However, analysis of the particle size distribution(More)