Ian Jeffrey

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The neurometabolic disorder glutaryl-CoA dehydrogenase (GCDH) deficiency is biochemically characterised by an accumulation of the marker metabolites 3-hydroxyglutaric acid, glutaric acid, and glutarylcarnitine. If untreated, the disease is complicated by acute encephalopathic crises, resulting in neurodegeneration of vulnerable brain regions, in particular(More)
BACKGROUND We recently demonstrated that increased expression of the RNA-binding protein RBM3 is associated with a favourable prognosis in breast cancer. The aim of this study was to examine the prognostic value of RBM3 mRNA and protein expression in epithelial ovarian cancer (EOC) and the cisplatin response upon RBM3 depletion in a cisplatin-sensitive(More)
—A scattering model based on a Monte Carlo method and the finite-volume time-domain (FVTD) method has been created for sea ice scattering simulations. Statistical methods were used to generate a Gaussian-distributed randomly rough surface. The Polder–Van Santen–de Loor (PVD) model was used to estimate the sea ice dielectric values with inputs based upon(More)
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