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Electrical recordings from the surface of the skull have a wide range of rhythmic components. A major task of analysis of this EEG is to determine their source and functional significance. The hippocampal "theta rhythm" has been extensively studied in rats and its rhythmicity has recently been shown to be functionally significant, per se. Here, we use(More)
Past research has found evidence for face and emotional expression processing differences between individuals with Asperger's syndrome (AS) and neurotypical (NT) controls at both the neurological and behavioural levels. The aim of the present study was to examine the neurophysiological basis of emotional expression processing in children and adults with AS(More)
Single-unit discharge was recorded from cells in the posterior hypothalamic nucleus (PH), supramammillary nucleus (SuM), and medial mammillary nucleus (MM) during hippocampal theta (theta) elicited by stimulation of the reticular nucleus pontis oralis (RPO). In agreement with previously published work, theta-related cells in the PH (12 cells) were all(More)
Long-term potentiation (LTP) is a candidate synaptic mechanism underlying learning and memory that has been studied extensively at the cellular and molecular level in laboratory animals. To date, LTP has only been directly demonstrated in humans in isolated cortical tissue obtained from patients undergoing surgery, where it displays properties identical to(More)
Extracellular multi-unit activity was recorded from sites in the supramammillary area of urethane anaesthetized rats, while simultaneously recording the hippocampal EEG. The pattern of supramammillary area cell discharge was found to be rhythmic and in phase with concurrent hippocampal rhythmical slow activity (RSA). Septal application of procaine (20%, 1-5(More)
The majority of studies support a role of the anterior cingulate cortex (ACC) in the attentional control necessary for conflict resolution in the Stroop task; however, the time course of activation and the neural substrates underlying the Stroop task remain contentious. We used high-density EEG to record visual-evoked potentials from 16 healthy subjects(More)
OBJECTIVES The aim of this study was to examine the N300 and N400 effect to pictures that were semantically incongruous to a prior object name. Based upon theories of object identification, the semantic incongruity was manipulated to occur early or late in the object processing stream. METHODS High-density visual event-related potentials were measured in(More)
1. Single-unit discharge patterns of cells in specific nuclei of the caudal diencephalon were characterized in relation to simultaneously recorded field activity from the stratum moleculare of the dentate gyrus according to the criteria that have been used previously to classify cells in the hippocampal formation (including entorhinal cortex), medial(More)
It is well established that the occurrence of theta rhythm in the hippocampus is important in a variety of mnemonic tasks. However, in this review it will be argued that theta-rhythmic activity occurs across distributed networks within the diencephalon and neocortex as well as the hippocampus, and functions to temporally coordinate activity in distributed(More)
Rats were implanted chronically with hippocampal recording electrodes, a microinfusion guide cannula aimed at the medial septal nucleus, and an electrode for electrical stimulation of the posterior hypothalamic nucleus (PH). PH stimulation elicited running in rats placed in a wheel and simultaneously occurring hippocampal theta field activity (HPC-theta).(More)