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avelength-division multiplexing (WDM) is currently being deployed in telecommunications networks in order to satisfy the increased demand for capacity brought about by both narrowband services and new broadband services such as high-speed Internet. While it is thought that WDM will ultimately evolve to interconnected rings or perhaps a mesh network, the(More)
Since aberrant miRNA expression has been implicated in numerous brain diseases, we studied miRNA expression and miRNA regulation of important signaling pathways during temporal lobe epileptogenesis in order to identify possible targets for epilepsy therapy. The temporal profile of miRNA expression was analyzed in three brain regions (CA1; dentate gyrus, DG;(More)
In this study, the oestrogen agonist/antagonist action of 4-hydroxytamoxifen (OHT; 1 x 10(-6) M) and 17beta-oestradiol (E(2); 1 x 10(-8) M) were assessed on the oestrogen receptor (ER)-positive epithelial cell line (Ishikawa) with respect to cell proliferation, and to gene and protein expression. qRT-PCR and western blotting confirmed that Ishikawa cells(More)
INTRODUCTION Long-term outcome of patients following conversion during laparoscopic surgery for colorectal cancer is not often reported. Recent data suggest a negative impact of conversion on long-term survival. This study aimed to evaluate the impact of conversion on the perioperative outcome and on long-term survival in patients who underwent laparoscopic(More)
An analysis of the sending rate of TCP control over Terabit per second rate links illustrates how future optical network characteristics, such as higher bitrates, network congestion, and larger data loads, would affect performance. We have implemented a model to allow increased sending rate for TCP. It is shown that even if the network bitrate is higher and(More)
IPTV services are the fastest growing television services in the world today. This is a bandwidth intensive service, requiring low latency and tight control of jitter. To guarantee the quality of service required, service providers opt to multicast all TV channels at all times to everywhere. However, a significant number of channels are rarely watched, so(More)
We present a local area sub-network design avoiding optical buffering, bit level synchronization and regeneration. Using currently available components we calculate acceptable utilisation when scalability is limited to local, system, storage and desk area networks. The architecture draws upon well-understood computer networking concepts, and uses wavelength(More)
One of the major concerns of IPTV network deployment is channel change delay (also known as zapping delay). This delay can add up to 2 s or more, and its main culprits are synchronisation and buffering of the media streams. Proving the importance of the problem is the already significant amount of literature addressing it. We start this paper with a survey(More)