Ian D Pitfield

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Model surfaces representative of chromatographic stationary phases were developed by immobilising an homologous series (C2-C18) of n-alkylthiols, mixed monolayers of C4/C18 and thioalkanes with alcohol, carboxylic acid, amino and sulphonic acid terminal groups onto a flat, silver-coated glass surface using self-assembled monolayer (SAM) chemistry. The(More)
'Multi-dimensional' liquid separations have a history almost as long as chromatography. In multi-dimensional chromatography the sample is subjected to more than one separation mechanism; each mechanism is considered an independent separation dimension. The separations can be carried out either offline via fraction collection, or directly coupled online.(More)
I. HARM REDUCTION: A KEY ELEMENT IN THE FIGHT AGAINST A DDICTION ............................................ 414 A. Change of Plans: The Switch from Prohibition to Harm Reduction and Safe Injection Facilities ................... 414 B. A Look at Successful Implementation in Other Countries ..... 417 1. Switzerland ...................................... 418(More)
The design, synthesis and chromatographic operation of a new range of stable and selective immobilized dye affinity adsorbents for potential application in the purification of pharmaceutical proteins is described. Computer aided molecular design has been exploited to design novel dye ligands which show a predictable selectivity for the target protein and(More)
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