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A multichannel statistical classifier for detecting prostate cancer was developed and validated by combining information from three different magnetic resonance (MR) methodologies: T2-weighted, T2-mapping, and line scan diffusion imaging (LSDI). From these MR sequences, four different sets of image intensities were obtained: T2-weighted (T2W) from(More)
Direct estimation of cardiac ventricular volumes has become increasingly popular and important in cardiac function analysis due to its effectiveness and efficiency by avoiding an intermediate segmentation step. However, existing methods rely on either intensive user inputs or problematic assumptions. To realize the full capacities of direct estimation, this(More)
Magnetic resonance imaging and optical microscopy are key technologies in the life sciences. For microbiological studies, especially of the inner workings of single cells, optical microscopy is normally used because it easily achieves resolution close to the optical wavelength. But in conventional microscopy, diffraction limits the resolution to about half(More)
STUDY OBJECTIVE Early diagnosis of children with meningitis or septicemia remains a significant challenge in emergency medicine. We seek to describe the frequency of repeated emergency department (ED) visits among children admitted with meningitis or septicemia in Ontario, Canada. METHODS In this retrospective cohort study, using health administrative(More)
Accurate estimation of ventricular volumes plays an essential role in clinical diagnosis of cardiac diseases. Existing methods either rely on segmentation or are restricted to direct estimation of the left ventricle. In this paper, we propose a novel method for direct and joint volume estimation of bi-ventricles, i.e., the left and right ventricles, without(More)
RATIONALE AND OBJECTIVES To prospectively evaluate the perceived image quality of model-based iterative reconstruction (MBIR) compared to adaptive statistical iterative reconstruction (ASIR) and filtered back-projection (FBP) in computed tomography (CT) of the kidneys and retroperitoneum. MATERIALS AND METHODS With investigational review board and Health(More)
Cardiac four-chamber volume estimation serves as a fundamental and crucial role in clinical quantitative analysis of whole heart functions. It is a challenging task due to the huge complexity of the four chambers including great appearance variations, huge shape deformation and interference between chambers. Direct estimation has recently emerged as an(More)
The diagnosis, comparative and population study of cardiac radiology data require heart segmentation on increasingly large amount of images from different modalities/chambers/patients under various imaging views. Most existing automatic cardiac segmentation methods are often limited to single image segmentation with regulated modality/region settings or(More)