Ian Benzeval

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To investigate whether permeation enhancement techniques affect the nail plate. Infrared and impedance spectroscopies examined the effects of hydration, iontophoresis and N-acetyl-L-cysteine on the human nail. While significant shifts to higher wavenumbers were observed for the symmetric and asymmetric -CH2 stretching vibrations these changes were(More)
Dextran solutions intended for use as plasma extenders have been observed to form insoluble precipitates. Earlier studies of precipitation have shown that in solutions of 50% and 60% w/w of dextran molecular mass 6000 g mol(-1) beaded precipitates are formed over a two-week period. This study considers dextran precipitation over a wider molecular mass range(More)
The interactions of a number of commercially available dextran preparations with the lectin concanavalin A (ConA) have been investigated. Dextrans over the molecular mass range 6x10 3 2x10 6 g mol -1 were initially characterised in terms of their branching, and hence terminal ligand density, using NMR. This showed a range of branching ratios between 3 and(More)
The interactions of a number of commercially available dextran preparations with the lectin Concanavalin A (ConA) have been investigated. Dextrans over the molecular mass range 6 × 10³-2 × 10⁶ g mol⁻¹ were initially characterised in terms of their branching and hence terminal ligand density, using NMR. This showed a range of branching ratios between 3% and(More)
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