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PIP4kγ is a substrate for mTORC1 that maintains basal mTORC1 signaling during starvation
- A. Mackey, Deborah A. Sarkes, I. Bettencourt, J. Asara, L. Rameh
- Biology, Medicine
- Science Signaling
- 4 November 2014
A feedback loop involving PIP4kγ and mTORC1 maintains basal mTORC1 activity under nutrient-deprived conditions. Maintaining a Basal Level of Activity Nutrients such as glucose and amino acids… Expand