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  • Elisa Izaurralde, Ulrike Kutay, Cayetano von Kobbe, Iain W Mattaj, Dirk Görlich
  • Medicine, Biology
  • The EMBO journal
  • 1997 (First Publication: 1 November 1997)
  • The GTPase Ran is essential for nuclear import of proteins with a classical nuclear localization signal (NLS). Ran's nucleotide-bound state is determined by the chromatin-bound exchange factor RCC1Continue Reading
  • Ulrike Kutay, Elisa Izaurralde, Francis Bischoff, Iain W Mattaj, Dirk Görlich
  • Medicine, Biology
  • The EMBO journal
  • 1997 (First Publication: 15 March 1997)
  • Nuclear protein import proceeds through the nuclear pore complex (NPC). Importin-beta mediates translocation via direct interaction with NPC components and carries importin-alpha with the NLSContinue Reading
  • Tobias C. Walther, Maarten Fornerod, Helen Pickersgill, Michal Goldberg, Terry D. Allen, Iain W Mattaj
  • Biology, Medicine, Chemistry
  • The EMBO journal
  • 2001 (First Publication: 15 October 2001)
  • The nuclear pore complex (NPC) is a large proteinaceous structure through which bidirectional transport of macromolecules across the nuclear envelope (NE) takes place. Nup153 is a peripheral NPCContinue Reading