Iain Burnett

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Current industry practices for large-scale mammalian cell cultures typically employ a standard platform fed-batch process with fixed volume bolus feeding. Although widely used, these processes are unable to respond to actual nutrient consumption demands from the culture, which can result in accumulation of by-products and depletion of certain nutrients.(More)
Ruthenium tetroxide and osmium tetroxide were compared as post-fixatives in the preparation of human epidermis for transmission electron microscopic examination. Both reagents revealed characteristic lamellar granules within the granular layer and extruded lamellar granule contents in the upper granular layer. The transformation of the granule contents into(More)
Decomposition of speech signals into periodic and noise components is widely used in speech coding to facilitate efficient compression. Existing decomposition schemes are too inflexible to model transient changes in the speech signal, require high delay or produce a large parameter set that is not scalable to low rates. This paper proposes a technique that(More)
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