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Isolation of dominant suppressor mutations for position-effect variegation in Drosophila melanogaster
SummaryDominant suppressor mutations for position-effect variegation have been isolated by using a strongly variegated line carrying the wm4 chromosome (wm4h) and the dominant enhancer mutant… Expand
Genotoxicological characterisation of complex mixtures. Genotoxic effects of a complex mixture of perhalogenated hydrocarbons.
Toxicological and genotoxicological investigation of complex mixtures is one of the main focus of the recent research in toxicology. Testing complex mixtures present a formidable scientific problem… Expand
Serum-free cryopreservation of porcine hepatocytes
The use of porcine hepatocytes in xenotransplantation, bioartificial liver support or pharmacological approaches demands serum-free cryopreservation protocols yielding high quality, viable,… Expand
Frequency of HPRT mutants in humans exposed to vinyl chloride via an environmental accident.
- R. Becker, T. Nikolova, I. Wolff, D. Lovell, E. Hüttner, H. Foth
- Chemistry, Medicine
- Mutation research
- 25 July 2001
The mutant frequency (MF) in the hypoxanthine-guanine-phosphoribosyl-transferase (HPRT) locus of peripheral blood T-lymphocytes was measured in a population environmentally exposed to vinyl chloride… Expand
Functional properties of the heterochromatic sequences inducing wm4position-effect variegation in Drosophila melanogaster
In position-effect variegation euchromatic genes are brought into the vicinity of heterochromatic sequences as a result of chromosomal rearrangements. This results in the inactivation of these genes… Expand
Micronuclei and Comet Assay
Publisher Summary This chapter discusses the role of micronuclei and comet assay in evaluating genotoxic effects of chemical substances in vitro. The micronucleus assay is one of the methods used to… Expand
GENETIC DIFFERENTIATION AMONG THREE SPECIES OF PARDOSA ( ARACHNIDA : L YCOSIDAE )
AlJozymic vanatlOn in nine protein producing loci was examined in three species of Pardosa using starch gel electrophoresis. Allozyme frequencies showed a high degree of geographic uniformity among… Expand