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Cell polyploidy: its relation to tissue growth and function.
Genome multiplication in growth and development : biology of polyploid and polytene cells
This authoritative account of the developmental biology of genome multiplication, the reproduction of the genetic material that results in polyploid and polytene cells, is based on many years' study by its authors and is particularly valuable in that it includes scientific results previously available only in Russian.
Mitotic polyploidization of mouse heart myocytes during the first postnatal week
It is concluded that cell multiplication is practically arrested at this period of life, and growth of the ventricular mass is due to polyploidization of virtually all cycling cells, while their number remains unchanged.
An improved method of mouse liver micronucleus analysis: an application to age-related genetic alteration and polyploidy study.
[Analysis of the postnatal growth of the mouse liver by estimating the hepatocyte count, their weight and ploidy].
Estimation of the contribution of different growth components: increase in cell number, hypertrophy and polyploidization of cells, to the total increase of the liver mass finds that derivative of all three growth components coincides fairly well with the factual changes in the livermass.
Detection of α-foetoprotein in mouse liver differentiated hepatocytes before their progression through S phase
- N. Engelhardt, M. Lazareva, G. Abelev, I. V. Uryvaeva, V. Factor, V. Brodsky
- Biology, MedicineNature
- 9 September 1976
The immunohistochemical localisation of AFP is described in regenerating mouse livers, in which DNA-synthesising cells have been identified by thymidine incorporation and DNA synthesis is not a prerequisite for the induction of AFP synthesis in the adult liver.
Biological significance of liver cell polyploidy: an hypothesis.
- I. V. Uryvaeva
- Biology, MedicineJournal of theoretical biology
- 21 April 1981
[Somatic polyploidy in tissue development].
Kinetics of cellular proliferation in regenerating mouse liver pretreated with the alkylating drug dipin
- V. Faktor, I. V. Uryvaeva, A. Sokolova, V. Chernov, W. Brodsky
- Biology, MedicineVirchows Archiv. B, Cell pathology including…
Pretreatment of resting liver with Dipin altered the kinetics of cell proliferation following partial hepatectomy, resulting in delay in division resulted primarily from an increase in the DNA-synthesis time and a prolonged block of the transition from G2 to mitosis.