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Pattern searches for the identification of putative lipoprotein genes in Gram-positive bacterial genomes.
N-terminal lipidation is a major mechanism by which bacteria can tether proteins to membranes and one which is of particular importance to Gram-positive bacteria due to the absence of a retentiveExpand
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A phylum level perspective on bacterial cell envelope architecture.
  • I. Sutcliffe
  • Biology, Medicine
  • Trends in microbiology
  • 1 October 2010
Improved understanding of the bacterial phylogenetic tree has allowed the distinction of at least 25 phyla with cultured representatives. This review surveys the diversity of cell envelope typesExpand
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Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em.
Gram-positive bacterial lipoproteins are a functionally diverse and important class of peripheral membrane proteins. Recent advances in molecular biology and the availability of whole genome sequenceExpand
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Methods for the bioinformatic identification of bacterial lipoproteins encoded in the genomes of Gram-positive bacteria
Bacterial lipoproteins are a diverse and functionally important group of proteins that are amenable to bioinformatic analyses because of their unique signal peptide features. Here we have used aExpand
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Lipoproteins of gram-positive bacteria.
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A binding protein-dependent transport system in Streptococcus mutans responsible for multiple sugar metabolism.
An 11-kilobase gene region of Streptococcus mutans has been identified which contains eight contiguous genes involved with the uptake and metabolism of multiple sugars (the msm system). SequenceExpand
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A novel lipoarabinomannan from the equine pathogen Rhodococcus equi. Structure and effect on macrophage cytokine production.
Rhodococcus equi is a major cause of foal morbidity and mortality. We have investigated the presence of lipoglycan in this organism as closely related bacteria, notably Mycobacterium tuberculosis,Expand
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Cell envelope composition and organisation in the genus Rhodococcus
  • I. Sutcliffe
  • Biology, Medicine
  • Antonie van Leeuwenhoek
  • 1 July 1998
A knowledge of the organisation of the rhodococcal cell envelope is of fundamental importance if the environmental and biotechnological significance of these bacteria are to be understood andExpand
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The molecular basis of Streptococcus equi infection and disease.
Streptococcus equi is the aetiological agent of strangles, one of the most prevalent diseases of the horse. The animal suffering and economic burden associated with this disease necessitate effectiveExpand
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Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria
The composition of the Gram-positive cell wall is typically described as containing peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids, which compriseExpand
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