• Publications
  • Influence
EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis
Background:  Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb).
The neurotropic herpes viruses: herpes simplex and varicella-zoster
The biological, medical, and neurological aspects of acute, latent, and reactivated infections with the neurotropic herpes viruses are reviewed. Expand
Viral meningoencephalitis: a review of diagnostic methods and guidelines for management
The prognosis depends mainly on the pathogen and host immunologic state and the correct immediate diagnosis and introduction of symptomatic and specific therapy. Expand
EFNS guideline on the management of community‐acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults
A consensus guideline was developed for initial management, investigations, antibiotics and supportive therapy of community‐acquired ABM and whenever possible, the choice of antibiotics, and the duration of therapy, should be guided by the microbiological diagnosis. Expand
Infectious causes of multiple sclerosis
Experimental allergic encephalomyelitis: A misleading model of multiple sclerosis
This review examines critically the validity that EAE is an adequate and useful animal model of MS and finds credible evidence lacking, and proposes to reconsider the utilization of EAE, especially when this model is used to define therapy. Expand
Lyme neuroborreliosis: infection, immunity, and inflammation
An appreciation of the genetic heterogeneity of the causative pathogen has helped clinicians in their understanding of the diverse presentations of LNB. Expand
Herpes simplex virus encephalitis: new infection or reactivation?
  • I. Steiner
  • Medicine
  • Current opinion in neurology
  • 1 June 2011
The present review covers the biological, medical, and neurological aspects of HSE, focusing among others on recent molecular findings of gene expression during latent infection of HSV-1. Expand
Herpes simplex virus type 1 latency‐associated transcripts are evidently not essential for latent infection.
The data indicate that detectable levels of these latency‐associated transcripts are not required for viral replication, establishment, or maintenance of HSV‐1 latency in trigeminal ganglia, but suggest a role in reactivation. Expand