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High resolution ΔR2, ΔR2*, and vessel density MRI of the rat ocular circulation
The vessel density index of the rat retina could serve as an alternative method of postmortem fluorescence microscopy-based vessel density measurement that has been widely used to characterize retinal and choroidal vascular degeneration or neovascularization in disease states.
Endogenous opioid-dopamine neurotransmission evokes sustained negative CBV-weighted fMRI responses
It is shown that the nociception-induced negative fMRI signals in the brain are driven by opioid–dopamine interactions, and that without either of these neurotransmitters the negative signals cannot be present.