I. Sherman

Publications279
h-index34
Citations5,104
Highly Influential Citations122
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Malaria : parasite biology, pathogenesis, and protection
A Brief History of Malaria and Discovery of the Parasite's Life Cycle The Current Global Malaria Situation Gametocytes and Sexual Development Sporogonic Development in the Mosquito Engineering… Expand
  • 759
  • 40
Biochemistry of Plasmodium (malarial parasites).
  • I. Sherman
  • Biology, Medicine
  • Microbiological reviews
  • 1 December 1979
  • 494
  • 15
Cytoadherence and sequestration in Plasmodium falciparum: defining the ties that bind.
Infected erythrocytes containing the more mature stages of the human malaria Plasmodium falciparum may adhere to endothelial cells and uninfected red cells. These phenomena, called sequestration and… Expand
  • 214
  • 11
  • PDF
Studies of Plasmodium falciparum cytoadherence using immortalized human brain capillary endothelial cells.
The cytoadherence of Plasmodium falciparum-infected erythrocytes was studied using immortalized human brain capillary endothelial cells. The immortalized cells, denoted as BB19, derived from the… Expand
  • 76
  • 4
Cytoadherence of Malaria-Infected Red Blood Cells Involves Exposure of Phosphatidylserine
Phosphatidylserine (PS) is a membrane phospholipid which in intact cells is exclusively localized in the inner leaflet of the lipid bilayer. However, once cells undergo apoptosis or oxidative stress,… Expand
  • 154
  • 3
Transport of amino acids and nucleic acid precursors in malarial parasites.
  • I. Sherman
  • Biology, Medicine
  • Bulletin of the World Health Organization
  • 1977
In vitro studies have shown that exogenously supplied amino acids are transferred into the malaria-infected cell, where they are incorporated into proteins. Most amino acids appear to enter the cell… Expand
  • 62
  • 2
Phospholipid composition, cholesterol content and cholesterol exchange in Plasmodium falciparum-infected red cells.
The membrane lipid composition and [3H]cholesterol exchange rate were studied in both normal human erythrocytes and those infected with the human malaria Plasmodium falciparum. The host cell membrane… Expand
  • 68
  • 2
Scanning electron microscope-analysis of the protrusions (knobs) present on the surface of Plasmodium falciparum-infected erythrocytes
The nature of the surface deformations of erythrocytes infected with the human malaria parasite Plasmodium falciparum was analyzed using scanning electron microscopy at two stages of the 48-h… Expand
  • 90
  • 2
  • PDF
Amino acid metabolism and protein synthesis in malarial parasites.
  • I. Sherman
  • Biology, Medicine
  • Bulletin of the World Health Organization
  • 1977
Malaria-infected red cells and free parasites have limited capabilities for the biosynthesis of amino acids. Therefore, the principal amino acid sources for parasite protein synthesis are the plasma… Expand
  • 109
  • 2
Plasmodium falciparum: pfalhesin and CD36 form an adhesin/receptor pair that is responsible for the pH-dependent portion of cytoadherence/sequestration.
The cytoadherent behavior of two Plasmodium falciparum (human malaria) cell lines, FCR-3 and ITO4 (a cell line with elevated ICAM-1 adherence), was studied using CHO cells transfected with CD36 or… Expand
  • 45
  • 2