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Acute toxicity, brine shrimp cytotoxicity and relaxant activity of fruits of callistemon citrinus curtis
TLDR
The screening of fractions of the crude methanol extract for tracing spasmolytic constituents so that it shall help us for isolation of bioactive compounds is described.
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Anthelmintic and relaxant activities of Verbascum Thapsus Mullein
TLDR
The authors' results suggest that V. thapsus, which is currently used by some tribes in the Malakand region of Pakistan, has anthelmintic and antispasmodic value.
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Analysis of total flavonoids and phenolics in different fractions of bark and needle extracts of Pinus roxburghii and Pinus wallichiana
Total flavonoid and phenolic content was estimated quantitatively by using colorimetric method in various fractions of bark and needle extracts of Pinus roxburghii and Pinus wallichiana . Flavonoids…
Pharmacological profile of the aerial parts of Rubus ulmifolius Schott
TLDR
It is confirmed that aerial parts of Rubus ulmifolius contain flavonoids that are safe up to 6 g/kg following oral doses for acute toxicity study and have significant antioxidant and antipyretic activity.
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Antioxidant and relaxant activity of fractions of crude methanol extract and essential oil of Artemisia macrocephala jacquem
TLDR
Crude methanol and its fractions (ethyl acetate, chloroform and butanol) are rich sources of antioxidant constituents and the relaxing constituents following calcium channel blocking mechanisms are more concentrated in n-hexane, chlorOform and ethyl acetate fractions that warrant isolation.
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Cytotoxic and anthelmintic potential of crude saponins isolated from Achillea Wilhelmsii C. Koch and Teucrium Stocksianum boiss
TLDR
The crude saponins of Achillea wilhelmsii and Teucrium stocksianum may be excellent sources of cytotoxic and anthelmintic constituents that warrant its isolation and purification for new drug development.
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Acute toxicity and antispasmodic activities of Achillea wilhelmsii C. Koch.
TLDR
Since Achillea wilhelmsii is used as antispasmodic in traditional medicine, the current work to investigate its rationale on scientific grounds and investigate its possible mode of action through calcium channels is conducted.
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Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability
TLDR
Results obtained showed that the synthesized amphiphile is biocompatible and has excellent capability for formation of niosomal vesicles and enhancing oral bioavailability of less water-soluble drugs like clarithromycin.
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Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem
TLDR
The results showed that the STLs of Artemisia macrocephala possesses promising antioxidant activity and also it decreased the viability of 3 T3, HeLa and MCF-7 cells and mild to moderate antinociceptive activity.
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Scientific investigation of crude alkaloids from medicinal plants for the management of pain
TLDR
Crude alkaloids of Woodfordia fruticosa and Peganum harmala showed prominent analgesic potentials through inhibition of peripheral as well as central nervous system mechanisms, and further work is required for isolation of the pharmacologically active constituents.
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