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Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus.
A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus
The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
The metabolism of the fluoroquinolone drugs ciprofloxacin and norfl oxacin by Pestalotiopsis guepini strain P-8 was investigated and the four transformation products from norfloxACin are all known to be mammalian metabolites.
Microbiological Transformation of Enrofloxacin by the Fungus Mucor ramannianus
Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones and three metabolites were identified.
Transformation of artemisinin by Cunninghamella elegans
7β-hydroxyartemisinin, obtained from microbial transformation, is utilized as a semi-synthetic precursor for the synthesis of novel 7β-substituted art Artemisinin anti-malarial agents.
Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus
To investigate the microbial biotransformation of veterinary fluoroquinolones, Mucor ramannianus was grown in sucrose/peptone broth with sarafloxacin for 18 days and the biological formation of desethylene-N-acetylsarafl Oxacin has not been previously observed.
Biocatalysis of the Antimalarial Artemisinin by Mucor ramannianus. Strains
Abstract Biocatalysis of artemisinin by different strains of Mucor ramannianus.* illustrates a simple approach to bioengineering for attaining useful biotransformation strains for preparative or
Microbial transformation of azaarenes and potential uses in pharmaceutical synthesis
Pyridine, quinoline, acridine, indole, carbazole, and other heterocyclic nitrogen-containing compounds (azaarenes) can be transformed by cultures of bacteria and fungi to produce a variety of new
Biotransformation of Steroids and Flavonoids by Cultures of Aspergillus niger
Biotechnological processes are being developed that use cultures of Aspergillus niger and other fungi to transform steroids and flavonoids to a variety of metabolites, which may be used for the production of higher-value compounds.
Microbial transformation of antimalarial terpenoids.
Formation of conjugates from ciprofloxacin and norfloxacin in cultures of Trichoderma viride
The formation of conjugates from two antibacterial fluoroquinolone drugs, ciprofloxacin and norfloxacin, was observed in cultures of Trichoderma viride that had been grown in sucrose-peptone broth