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Clinical and neurocognitive predictors of functional outcome in bipolar euthymic patients: a long-term, follow-up study.
TLDR
Subdepressive symptomatology together with neurocognitive impairments related to verbal memory and executive functions are predictor variables of long-term functional outcome in bipolar disorder. Expand
The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders.
TLDR
A consensus was reached on 12 statements on the use of antidepressants in bipolar disorder, and antidepressants should be prescribed only as an adjunct to mood-stabilizing medications. Expand
Clinical and therapeutic implications of predominant polarity in bipolar disorder.
TLDR
Prevention of depression is crucial for the maintenance treatment of bipolar II patients, whilst prevention of mania and depression would be equally important in the case of bipolar I patients, and Predominant polarity is a valid prognostic parameter with therapeutic implications. Expand
Melancholia agitata and mixed depression
TLDR
The diagnostic entity of major depressive episode includes both simple and agitated or mixed depression, which is characterized by a full depressive episode with several symptoms of excitatory nature. Expand
Efficacy of functional remediation in bipolar disorder: a multicenter randomized controlled study.
TLDR
Functional remediation showed efficacy in improving the functional outcome of a sample of euthymic bipolar patients as compared with treatment as usual, suggesting an interaction between treatment assignment and time. Expand
Assessment and management of agitation in psychiatry: Expert consensus
TLDR
Recommendations on the assessment of agitation emphasise the importance of identifying any possible medical cause and the “ideal” medication should calm without over-sedate. Expand
New treatment guidelines for acute bipolar depression: a systematic review.
TLDR
The management of bipolar depression is complex and should be differentiated from management of unipolar depression, and the latest updates on treatment guidelines for bipolar depression give priority to novel treatment approaches, such as quetiapine, over more traditional ones,such as lithium or antidepressants. Expand
Mood stabilizers and antipsychotics during breastfeeding: Focus on bipolar disorder
TLDR
The available data supports the use of lithium as a possible treatment option during breastfeeding and quetiapine and olanzapine should be considered as first-line treatment options. Expand
Gender differences in a cohort study of 604 bipolar patients: the role of predominant polarity.
TLDR
The main characteristic featuring bipolar women is depression, both at illness onset and as a predominant polarity all along the illness course, which may have important diagnostic and therapeutic implications. Expand
Suicidal risk factors in bipolar I and II disorder patients.
TLDR
Suicidal risk-factors found to be independent of bipolar disorder diagnostic subtype included mixed-states, melancholic depressive features, and more antidepressant trials. Expand
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