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Transection of the oesophagus for bleeding oesophageal varices
- R. Pugh, I. Murray-Lyon, J. Dawson, M. Pietroni, Roger M. Williams
- The British journal of surgery
- 1 August 1973
Emergency ligation of bleeding oesophageal varices using the Milnes Walker technique was performed in 38 patients, and in patients with good preoperative liver function this rose to 71% and the simple scoring system for grading the severity of disturbance of liver function was found to be of value in predicting the outcome of surgery. Expand
Indications, methods, and outcomes of percutaneous liver biopsy in England and Wales: an audit by the British Society of Gastroenterology and the Royal College of Physicians of London.
- I. Gilmore, A. Burroughs, I. Murray-Lyon, R. Williams, D. Jenkins, A. Hopkins
- 1 March 1995
Day case biopsy and techniques to reduce the risk of bleeding were surprisingly rare in this series, which has given a unique opportunity to examine everyday practice across a wide range of hospitals. Expand
Evaluation of a modified commercial assay in detecting antibody to hepatitis C virus in oral fluids and dried blood spots
Oral fluids collected by the OraSure device provide an extremely useful method to conduct public health surveillance of not only HIV, but also hepatitis C, among injecting drug users, and dried blood spot specimens may be useful for surveillance and could be employed as a first line diagnostic specimen. Expand
Natural history of hepatic sarcoidosis and its response to treatment
- P. Kennedy, N. Zakaria, +5 authors J. Devlin
- European journal of gastroenterology & hepatology
- 1 July 2006
Sarcoidosis can cause end-stage chronic liver disease, which is often unrecognized until examination of the explanted liver, and response to conventional immunosuppression is variable and unpredictable. Expand
Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions.
- S. Khakoo, P. Glue, +8 authors G. Dusheiko
- British journal of clinical pharmacology
- 1 December 1998
There was no evidence of pharmacokinetic interactions between interferon alpha-2b and ribavirin in patients with chronic hepatitis C infections and the safety profile of combination therapy was similar to those of both monotherapy treatments. Expand
Plasma cathinone levels following chewing khat leaves (Catha edulis Forsk.).
Controlled trial of prednisone and azathioprine in active chronic hepatitis.
Abstract A double-blind prospective trial of prednisone versus azathioprine in the treatment of forty-seven patients with active chronic hepatitis over a 2-year period showed that prednisone was… Expand
Causes of death in fulminant hepatic failure and relationship to quantitative histological assessment of parenchymal damage.
- B. Gazzard, B. Portmann, I. Murray-Lyon, R. Williams
- The Quarterly journal of medicine
- 1 October 1975
Observations suggest that many patients presently dying from fulminant hepatic failure may be expected to survive, once more effective therapy is available for the complications of the illness. Expand
Plasma and brain amino acids in fulminant hepatic failure and their relationship to hepatic encephalopathy.
- C. Record, B. Buxton, R. Chase, G. Curzon, I. Murray-Lyon, R. Williams
- Biology, Medicine
- European journal of clinical investigation
- 1 February 1976
Brain to plasma ratios of most amino acids in hepatic coma patients were similar to control subjects suggesting that plasma concentration is the main factor controlling the cerebral concentration, however, for the branched chain amino acids, cerebrospinal fluid and brain concentrations were increased when plasma concentrations were normal suggesting an increase in brain uptake. Expand
Histopathological changes in the liver following a paracetamol overdose: Correlation with clinical and biochemical parameters
- B. Portmann, I. Talbot, D. Day, A. R. Davidson, I. Murray-Lyon, R. Williams
- The Journal of pathology
- 1 November 1975
The histological recovery in even the most severe cases was remarkable, and only one of the 17 survivors whose initial biopsy showed the pattern of interlobular bridging necrosis had appreciable residual fibrosis in a follow-up biopsy taken after 1 yr. Expand