I. Mononen

Publications104
h-index26
Citations2,154
Highly Influential Citations47
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • V. Kaartinen
  • 156 Publications • 7,442 Citations
  • L. Peltonen
  • 920 Publications • 117,373 Citations
  • P. Aula
  • 205 Publications • 6,002 Citations
  • E. Diamandis
  • 1,222 Publications • 50,146 Citations
  • Publications
  • Influence
A longitudinal study of serum 25-hydroxyvitamin D and intact parathyroid hormone levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosis
TLDR
There is an inverse relationship between serum vitamin D level and MS clinical activity and the endocrine circuitry regulating serum calcium may be altered in MS. Expand
25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis
TLDR
It is concluded that the vitamin D stores in most MS patients are adequate for their normal bone metabolism, but lower vitamin D levels during MS relapses than in remission suggest that vitamin D could be involved in the regulation of the clinical disease activity of MS. Expand
Serum eosinophil cationic protein (ECP) and eosinophil protein X (EPX) in childhood asthma: The influence of atopy
The purpose of this study was to determine the value of serum measurements of eosinophil cationic protein (ECP) and eosinophil protein X (EPX) in diagnosing asthma in children, and to investigate the… Expand
Enzyme replacement therapy in a mouse model of aspartylglycosaminuria
TLDR
Findings suggest that AGU may be correctable by enzyme therapy, and suggest that the pathophysiologic characteristics of AGU were effectively corrected in non‐neuronal tissues ofAGU mice during 2 wk of AGA therapy. Expand
Twenty-four-month α-galactosidase A replacement therapy in Fabry disease has only minimal effects on symptoms and cardiovascular parameters
TLDR
ERT has only minimal effect on symptoms and cardiovascular morphology and function in Fabry disease, and larger ERT studies are warranted, especially in women, to solve current open questions, such as the age at which ERT should be started, optimal dosage and intervals between infusions. Expand
Glycosaparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline.
TLDR
The apparent active site of human leukocyte glycoasparaginase has been studied by labeling with an asparagine analogue, 5-diazo-4-oxo-L-norvaline, indicating that this inhibitor binds to the active site or very close to it. Expand
Vascular adhesion protein‐1 in human ischaemic stroke
TLDR
The results imply that by inducing SSAO‐derived toxic metabolites, VAP‐1 might aggravate ischaemic vascular changes, and the subsequent release of sV AP‐1 into circulation could be further examined as a potential marker of early ischaemia vasculopathy. Expand
Substrate specificity and reaction mechanism of human glycoasparaginase. The N-glycosidic linkage of various glycoasparagines is cleaved through a reaction mechanism similar to L-asparaginase.
TLDR
Results indicate that glycoasparaginase reacts as an exo-hydrolase toward the L-asparagine moiety of the substrates and the free alpha-amino and alpha-carboxyl groups are required for the enzyme reaction. Expand
Echocardiography in Fabry disease: diagnostic value of endocardial border binary appearance
TLDR
This work has shown that the endocardium in Fabry disease has a binary appearance on transthoracic echocardiography and this sign could be used with good accuracy to differentiateFabry disease from hypertrophic cardiomyopathy and even as a first filter to screen for suspected Faby disease. Expand
Gas chromatography analysis of cellular fatty acids and neutral monosaccharides in the identification of lactobacilli
TLDR
The results indicate that basic hydrolysis gave more comprehensive information about the fatty acids, but the analysis of monosaccharides was found to be much more useful in distinguishing between different species of lactobacilli. Expand
...
1
2
3
4
5
...