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Understanding of human ATP binding cassette superfamily and novel multidrug resistance modulators to overcome MDR.
- I. Mohammad, W. He, L. Yin
- Biology, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 April 2018
Indeed, multi-drug resistance (MDR) is a significant obstacle to effective chemotherapy. The overexpression of ATP-binding cassette (ABC) membrane transporters is a principal cause of enhanced… Expand
Molecular Alteration Analysis of Human Gut Microbial Composition in Graves' disease Patients
- Hafiz Muhammad Ishaq, I. Mohammad, +6 authors J. Xu
- Biology, Medicine
- International journal of biological sciences
- 7 September 2018
The gut microbial association with host co-existence is critical for body homeostasis and pathogenicity. Graves' disease (GD) is an autoimmune disease manifested with hyperthyroidism and… Expand
Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice
- Q. Du, S. Zhang, A. Li, I. Mohammad, B. Liu, Yanwu Li
- Chemistry, Medicine
- Front. Physiol.
- 23 January 2018
Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with… Expand
Phytocosmeceutical formulation development, characterization and its in-vivo investigations.
- I. Mohammad, M. Naveed, +7 authors H. Khan
- Chemistry, Art
- Biomedicine & pharmacotherapy = Biomedecine…
- 20 September 2018
Several plants found rich in flavonoid, polyphenols, and antioxidants reported antiaging, oppose inflammation and carcinogenic properties but have rarely been applied in dermatology. The present… Expand
Moisturizing effect of stable cream containing Crocus sativus extracts.
- N. Akhtar, H. Khan, S. Ashraf, I. Mohammad, Najam-us Saqib, K. Bashir
- Chemistry, Medicine
- Pakistan journal of pharmaceutical sciences
- 1 November 2014
The present study is about to prepare stable cream of water-in-oil emulsion containing extracts of Crocus sativus against its base (without extracts) taken as control, to determine its stability on… Expand
Significance of Prescription Elements and Reasons of Prescription Errors in South Punjab, Pakistan
Background: Prescription is a paper or electronic document issued by licensed medical practitioner detailing the medicine or medicines to be dispensed for an individually named patient. The objective… Expand
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A Smart Paclitaxel-Disulfiram Nanococrystals for Efficient MDR Reversal and Enhanced Apoptosis
- I. Mohammad, W. He, L. Yin
- Chemistry, Medicine
- Pharmaceutical Research
- 27 February 2018
PurposeA multidrug resistance (MDR) modulator, disulfiram (DSF), was incorporated into pure paclitaxel (PTX) nanoparticles to construct a smart paclitaxel-disulfiram nanococrystals (PTX-DSF Ns)… Expand
Molecular estimation of alteration in intestinal microbial composition in Hashimoto's thyroiditis patients.
- Hafiz Muhammad Ishaq, I. Mohammad, +7 authors J. Xu
- Biology, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 November 2017
The gut microbiota has a crucial effect on human health and physiology. Hypothyroid Hashimoto's thyroiditis (HT) is an autoimmune disorder manifested with environmental and genetic factors. However,… Expand
A novel ventricular restraint device (ASD) repetitively deliver Salvia miltiorrhiza to epicardium have good curative effects in heart failure management.
- M. Naveed, Li Wen-hua, +14 authors Zhou Xiaohui
- Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 November 2017
A novel ventricular restraint is the non-transplant surgical option for the management of an end-stage dilated heart failure (HF). To expand the therapeutic techniques we design a novel ventricular… Expand
Drug nanocrystals: Fabrication methods and promising therapeutic applications.
- I. Mohammad, H. Hu, L. Yin, W. He
- Chemistry, Medicine
- International journal of pharmaceutics
- 1 May 2019
The drug nanocrystals (NCs) with unique physicochemical properties are now considered as a promising drug delivery system for poorly water-soluble drugs. So far >20 formulations of NCs have been… Expand