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Recombinant allergen-based IgE testing to distinguish bee and wasp allergy.
Hom s 4, an IgE-Reactive Autoantigen Belonging to a New Subfamily of Calcium-Binding Proteins, Can Induce Th Cell Type 1-Mediated Autoreactivity1
Hom s 4-induced IFN-γ production was found in normal individuals, in patients with chronic inflammatory skin diseases and in Th2-prone atopic persons, suggesting that Hom s 4 represents a protein with an intrinsic property to induce Th1-mediated autoreactivity.
Linking allergy to autoimmune disease.
α-NAC–Specific Autoreactive CD8+ T Cells in Atopic Dermatitis Are of an Effector Memory Type and Secrete IL-4 and IFN-γ
The observed phenotype of α-NAC–specific CD8+ T cells indicates a role in the pathogenesis of AD, and the frequency and inflammatory phenotype of autoallergen-specific T cells is investigated.
The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.
The data demonstrate that the Hom s 2 autoantigen can cause IFN-gamma-mediated cell damage and could be inhibited with a neutralizing anti-IFN-Gamma antibody.
Low sensitivity of commercially available rApi m 1 for diagnosis of honeybee venom allergy.
High sensitivity of CAP-FEIA rVes v 5 and rVes v 1 for diagnosis of Vespula venom allergy.