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Mitigation strategies for pandemic influenza in the United States.
Recent human deaths due to infection by highly pathogenic (H5N1) avian influenza A virus have raised the specter of a devastating pandemic like that of 1917-1918, should this avian virus evolve toExpand
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Containing Pandemic Influenza at the Source
Highly pathogenic avian influenza A (subtype H5N1) is threatening to cause a human pandemic of potentially devastating proportions. We used a stochastic influenza simulation model for rural SoutheastExpand
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Containing pandemic influenza with antiviral agents.
For the first wave of pandemic influenza or a bioterrorist influenza attack, antiviral agents would be one of the few options to contain the epidemic in the United States until adequate supplies ofExpand
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FluTE, a Publicly Available Stochastic Influenza Epidemic Simulation Model
Mathematical and computer models of epidemics have contributed to our understanding of the spread of infectious disease and the measures needed to contain or mitigate them. To help prepare for futureExpand
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The Transmissibility and Control of Pandemic Influenza A (H1N1) Virus
Flu's Tricky Tricks After vaccination against influenza A virus, single-point mutations are selected in hemagglutinin (the virus molecule that binds to sialic acid molecules on the surface of hostExpand
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The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Outbreak to pandemic In response to global dispersion of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), quarantine measures have been implemented around the world. To understand howExpand
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Critical Factors Influencing the Occurrence of Vibrio cholerae in the Environment of Bangladesh
ABSTRACT The occurrence of outbreaks of cholera in Africa in 1970 and in Latin America in 1991, mainly in coastal communities, and the appearance of the new serotype Vibrio cholerae O139 in India andExpand
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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial
BACKGROUND A recombinant, replication-competent vesicular stomatitis virus-based vaccine expressing a surface glycoprotein of Zaire Ebolavirus (rVSV-ZEBOV) is a promising Ebola vaccine candidate. WeExpand
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Modeling targeted layered containment of an influenza pandemic in the United States
Planning a response to an outbreak of a pandemic strain of influenza is a high public health priority. Three research groups using different individual-based, stochastic simulation models haveExpand
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A mathematical model for the global spread of influenza
Abstract A mathematical model is presented for forecasting the global spread of influenza based on information from the initial city in the transportation network to experience the disease. ThisExpand
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