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- Publications
- Influence
Mitigation strategies for pandemic influenza in the United States.
- T. Germann, K. Kadau, I. Longini, C. Macken
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 11 April 2006
Recent human deaths due to infection by highly pathogenic (H5N1) avian influenza A virus have raised the specter of a devastating pandemic like that of 1917-1918, should this avian virus evolve to… Expand
Containing Pandemic Influenza at the Source
- I. Longini, A. Nizam, +4 authors M. Halloran
- Medicine
- Science
- 12 August 2005
Highly pathogenic avian influenza A (subtype H5N1) is threatening to cause a human pandemic of potentially devastating proportions. We used a stochastic influenza simulation model for rural Southeast… Expand
Containing pandemic influenza with antiviral agents.
- I. Longini, M. Halloran, A. Nizam, Y. Yang
- Medicine
- American journal of epidemiology
- 1 April 2004
For the first wave of pandemic influenza or a bioterrorist influenza attack, antiviral agents would be one of the few options to contain the epidemic in the United States until adequate supplies of… Expand
FluTE, a Publicly Available Stochastic Influenza Epidemic Simulation Model
- D. Chao, M. Halloran, Valerie J. Obenchain, I. Longini
- Biology, Computer Science
- PLoS Comput. Biol.
- 1 January 2010
Mathematical and computer models of epidemics have contributed to our understanding of the spread of infectious disease and the measures needed to contain or mitigate them. To help prepare for future… Expand
The Transmissibility and Control of Pandemic Influenza A (H1N1) Virus
- Y. Yang, Jonathan D Sugimoto, +6 authors I. Longini
- Medicine
- Science
- 30 October 2009
Flu's Tricky Tricks After vaccination against influenza A virus, single-point mutations are selected in hemagglutinin (the virus molecule that binds to sialic acid molecules on the surface of host… Expand
The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
- Matteo Chinazzi, Jessica Davis, +13 authors A. Vespignani
- Geography, Medicine
- Science
- 6 March 2020
Outbreak to pandemic In response to global dispersion of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), quarantine measures have been implemented around the world. To understand how… Expand
Critical Factors Influencing the Occurrence of Vibrio cholerae in the Environment of Bangladesh
- A. Huq, R. Sack, +10 authors R. Colwell
- Medicine, Biology
- Applied and Environmental Microbiology
- 1 August 2005
ABSTRACT The occurrence of outbreaks of cholera in Africa in 1970 and in Latin America in 1991, mainly in coastal communities, and the appearance of the new serotype Vibrio cholerae O139 in India and… Expand
Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial
- A. M. Henao-Restrepo, I. Longini, M. Egger, N. Dean, J. Røttingen
- Medicine
- The Lancet
- 29 August 2015
BACKGROUND
A recombinant, replication-competent vesicular stomatitis virus-based vaccine expressing a surface glycoprotein of Zaire Ebolavirus (rVSV-ZEBOV) is a promising Ebola vaccine candidate. We… Expand
Modeling targeted layered containment of an influenza pandemic in the United States
- M. Halloran, N. Ferguson, +14 authors P. Cooley
- Medicine, Psychology
- Proceedings of the National Academy of Sciences
- 25 March 2008
Planning a response to an outbreak of a pandemic strain of influenza is a high public health priority. Three research groups using different individual-based, stochastic simulation models have… Expand
A mathematical model for the global spread of influenza
- Leonid A. Rvachev, I. Longini
- Mathematics
- 1 July 1985
Abstract A mathematical model is presented for forecasting the global spread of influenza based on information from the initial city in the transportation network to experience the disease. This… Expand