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Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage.
Cytogenetic assays in peripheral blood lymphocytes (PBL) have been used extensively to survey the exposure of humans to genotoxic agents. The conceptual basis for this has been the hypothesis thatExpand
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Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. European Study Group on Cytogenetic Biomarkers and Health.
An increased risk of cancer in healthy individuals with high levels of chromosomal aberrations (CAs) in peripheral blood lymphocytes has been described in recent epidemiological studies. ThisExpand
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Chromosome aberrations in lymphocytes of high-voltage laboratory cable splicers exposed to electromagnetic fields.
Thirteen high-voltage laboratory employees and 20 referents participated in a cross-sectional, matched-pairs study of cytogenetic damage. During cable testing the workers were exposed to static,Expand
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Cytogenetic screening of a new‐born population
Chromosomes were analysed using banding techniques in 1830 consecutively born infants. The prevalence of chromosomal aberrations was 19.67 per 1000, which is higher than figures found in previousExpand
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An inter-Nordic prospective study on cytogenetic endpoints and cancer risk. Nordic Study Group on the Health Risk of Chromosome Damage.
To investigate whether high rates of chromosomal aberrations (CAs), sister chromatid exchange (SCE), or micronuclei(MN) in peripheral lymphocytes indicate an increased risk for subsequent cancer, aExpand
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Immortalization of normal human kidney epithelial cells by nickel(II).
The occupational and environmental hazards of nickel exposure are of great concern in environmental medicine. Nickel workers have increased risk of cancer of the nose, lung, larynx, and possibly theExpand
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Chromosome damage in lymphocytes of stainless steel welders related to past and current exposure to manual metal arc welding fumes.
Cytogenetic damage was studied in lymphocytes from 42 welders using the manual metal arc (MMA) method on stainless steel (SS). A detailed characterization of previous exposure by job interviews, andExpand
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Prader-Willi syndrome in a brother and sister without cytogenetic or detectable molecular genetic abnormality at chromosome 15q11q13.
We report on a 12-year-old boy and his 7-year-old sister with the Prader-Willi syndrome. They both had severe initial hypotonia with feeding problems and later developed an increasing appetite. BothExpand
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Chromosome aberrations in tunnel workers exposed to acrylamide and N-methylolacrylamide.
OBJECTIVES The aim of this study was to examine chromosome aberrations in 25 tunnel workers exposed to acrylamide-containing grout in injection work. METHODS Blood samples were collected from 25Expand
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A cytogenetic and haematological investigation of oil exposed workers in a Norwegian cable manufacturing company.
Cytogenetic and haematological parameters were studied in 31 oil exposed workers and 31 office workers matched for age and smoking, all men employed by a Norwegian cable manufacturing company.Expand
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