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Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse
Location, location, location. The Na-K pump of skeletal muscle is regulated differently at neuromuscular junctions.
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Na+,K+-ATPase Functionally Interacts with the Plasma Membrane Na+,Ca2+ Exchanger to Prevent Ca2+ Overload and Neuronal Apoptosis in Excitotoxic Stress
Using a fluorescent viability assay, immunocytochemistry, patch-clamp recordings, and Ca2+ imaging analysis, we report that ouabain, a specific ligand of the Na+,K+-ATPase cardiac glycoside bindingExpand
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The Nicotinic Acetylcholine Receptor and the Na,K-ATPase α2 Isoform Interact to Regulate Membrane Electrogenesis in Skeletal Muscle*
The nicotinic acetylcholine receptor (nAChR) and the Na,K-ATPase functionally interact in skeletal muscle (Krivoi, I. I., Drabkina, T. M., Kravtsova, V. V., Vasiliev, A. N., Eaton, M. J., Skatchkov,Expand
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Chronic Nicotine Modifies Skeletal Muscle Na,K-ATPase Activity through Its Interaction with the Nicotinic Acetylcholine Receptor and Phospholemman
Our previous finding that the muscle nicotinic acetylcholine receptor (nAChR) and the Na,K-ATPase interact as a regulatory complex to modulate Na,K-ATPase activity suggested that chronic, circulatingExpand
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Specialized Functional Diversity and Interactions of the Na,K-ATPase
Na,K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal cells and vitally essential for their functions. A specialized functional diversity of the Na,K-ATPase isozymes isExpand
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Isoform-Specific Na,K-ATPase Alterations Precede Disuse-Induced Atrophy of Rat Soleus Muscle
This study examines the isoform-specific effects of short-term hindlimb suspension (HS) on the Na,K-ATPase in rat soleus muscle. Rats were exposed to 24–72 h of HS and we analyzed the consequences onExpand
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Synaptic feed-backs mediated by potassium ions.
Repetitive activity of the neuromuscular system and of neuronal centers leads to K+ efflux from excited cells and to its accumulation within extracellular spaces and synaptic clefts, especiallyExpand
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Functional interactions of Na,K-ATPase with molecular environment
  • I. Krivoi
  • Medicine, Chemistry
  • Biofizika
  • 12 December 2014
The present review covers the analysis of research in the field of intermolecular interactions of Na,K-ATPase which underlie novel cellular regulatory mechanisms. The capability of Na,K-ATPase toExpand
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Decrease in the electrogenic Contribution of Na,K-ATPase and the resting membrane potential as a possible mechanism of Ca2+ accumulation in rat soleus muscle in a short-term gravity unloading
The resting membrane potential and electrogenic contribution of α1- and α2-isoforms of Na+/K+-ATPase in the rat soleus muscle at early stages of gravity unloading were analyzed. The role of L-typeExpand
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On the functional interaction between nicotinic acetylcholine receptor and Na+,K+-ATPase
Previous studies have shown that nanomolar acetylcholine (ACh) produces a 2 to 4-mV hyperpolarization of skeletal muscle fibers putatively due to Na+,K+-ATPase activation. The present studyExpand
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