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Different functions of HetR, a master regulator of heterocyst differentiation in Anabaena sp. PCC 7120, can be separated by mutation.
TLDR
Analysis of the heterocyst pattern in the hetRR223W mutant revealed that heterocysts differentiate essentially randomly along filaments, indicating that this mutation results in an active protein that is insensitive to the major signals governing heterocySt pattern formation.
hetC, a gene coding for a protein similar to bacterial ABC protein exporters, is involved in early regulation of heterocyst differentiation in Anabaena sp. strain PCC 7120
Transposon-generated mutant C3 of Anabaena sp. strain PCC 7120 is unable to form heterocysts upon deprivation of combined nitrogen but forms a pattern of spaced, weakly fluorescent cells after 2 days
Identification and Inactivation of Three Group 2 Sigma Factor Genes in Anabaena sp. Strain PCC 7120
TLDR
Phylogenetic analysis of cyanobacterial group 2 sigma factor sequences revealed that they fall into several subgroups, which is perhaps specific for filamentous or heterocystous cyanobacteria.
Lipopolysaccharide dependence of cyanophage sensitivity and aerobic nitrogen fixation in Anabaena sp. strain PCC 7120
TLDR
The results suggest that modified LPS may prevent cyanophage infection of Anabaena sp.
A gene cluster that regulates both heterocyst differentiation and pattern formation in Anabaena sp. strain PCC 7120
TLDR
The presence of homologous clusters in filamentous genera without heterocysts is suggestive of a more general role in co‐ordination of heterocyst differentiation and pattern formation.
Evidence that the hanA gene coding for HU protein is essential for heterocyst differentiation in, and cyanophage A-4(L) sensitivity of, Anabaena sp. strain PCC 7120
TLDR
Repeated subculturing of AB22 resulted in improved growth and loss of filament fragmentation, presumably because of one or more compensatory mutations; however, the mutant retained its A-4(L)r Het- phenotype.
2-Aminoadenine is an adenine substituting for a base in S-2L cyanophage DNA
TLDR
The isolation and identification of the base 2-aminoadenine and its deoxyribonucleoside from S-2L cyanophage DNA is reported and some unusual properties of this DNA in which adenine is completely substituted with 2-AMB are described.
Ancient association of cyanobacterial multicellularity with the regulator HetR and an RGSGR pentapeptide‐containing protein (PatX)
TLDR
Two proteins have been identified in the filamentous, heterocyst‐forming cyanobacterium, Anabaena PCC 7120 as the transcriptional regulator, HetR and the second as the small protein, PatS, which contains a critical RGSGR motif that binds toHetR.
Inactivation of Three RG(S/T)GR Pentapeptide-Containing Negative Regulators of HetR Results in Lethal Differentiation of Anabaena PCC 7120
TLDR
The mutational analysis has been interpreted in light of the opposing roles of negative regulators of HetR and the positive regulator HetL, suggesting that tight control over HetS and PatX is needed to sustain vegetative growth and regulated development.
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