• Publications
  • Influence
Genotoxic, cytostatic, antineoplastic and apoptotic effects of newly synthesized antitumour steroidal esters.
In this study, we have investigated the genotoxic, cytostatic, antineoplastic and apoptotic effects of three newly synthesized modified steroidal esters, having as alkylating agentExpand
  • 21
Cytogenetic and antineoplastic effects of modified steroidal alkylators.
INTRODUCTION The aim of this study was to design new potentially antineoplastic agents by combining nitrogen mustard with steroidal skeleton, in an effort to improve specificity and simultaneously toExpand
  • 10
Comparison of new nitrosoureas esters with modified steroidal nucleus for cytogenetic and antineoplastic activity.
Nitrosourea is decomposed under physiological conditions to react with biological macromolecules by two mechanisms: alkylation (with proteins and nucleic acids) and carbamoylation (with proteins butExpand
  • 8