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Structural analysis of tethered bilayer lipid membranes.
Solid supported membrane systems have been established as biomimetic architectures, which allow for the systematic investigation of various membrane-related processes. Especially tethered bilayerExpand
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Membrane on a chip: a functional tethered lipid bilayer membrane on silicon oxide surfaces.
Tethered membranes have been proven during recent years to be a powerful and flexible biomimetic platform. We reported in a previous article on the design of a new architecture based on theExpand
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Functional incorporation of the pore forming segment of AChR M2 into tethered bilayer lipid membranes.
Tethered bilayer lipid membranes (tBLMs) are robust and flexible model platforms for the investigation of various membrane related processes. They are especially suited to study the incorporation andExpand
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Tethered bimolecular lipid membranes - A novel model membrane platform
Abstract This contribution summarizes some of our efforts in designing, synthesizing, assembling, and characterizing functional tethered bimolecular lipid membranes (tBLMs) as a novel platform forExpand
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Stable insulating tethered bilayer lipid membranes
Tethered bilayer lipid membranes have been shown to be an excellent model system for biological membranes. Coupling of a membrane to a solid supports creates a stable system that is accessible forExpand
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Functional Ion Channels in Tethered Bilayer Membranes—Implications for Biosensors
The demand for rapid in situ detection of chemical and biological analytes has increased the interest in the development of biosensors, which combine biological sensing elements with physicochemicalExpand
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Membrane–drug interactions studied using model membrane systems
The direct interaction of drugs with the cell membrane is often neglected when drug effects are studied. Systematic investigations are hindered by the complexity of the natural membrane and modelExpand
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Tethered and Polymer Supported Bilayer Lipid Membranes: Structure and Function
Solid supported bilayer lipid membranes are model systems to mimic natural cell membranes in order to understand structural and functional properties of such systems. The use of a model system allowsExpand
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Formation of tethered bilayer lipid membranes probed by various surface sensitive techniques
Tethered bilayer lipid membranes are promising biomimetic architectures. Their formation has been investigated using four different surface sensitive techniques, including optical, acoustic, andExpand
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Assembly of the m2 tetramer is strongly modulated by lipid chain length.
The influenza virus matrix protein 2 (M2) assembles into a tetramer in the host membrane during viral uncoating and maturation. It has been used as a model system to understand the relativeExpand
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