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A voxel-based morphometric study of ageing in 465 normal adult human brains
Voxel-based-morphometry (VBM) is a whole-brain, unbiased technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resonance images. WeExpand
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Global grey matter volume decreased linearly with age, with a significantly steeper decline in males, and local areas of accelerated loss were observed bilaterally in the insula, superior parietal gyri, central sulci, and cingulate sulci. Expand
Cerebral Asymmetry and the Effects of Sex and Handedness on Brain Structure: A Voxel-Based Morphometric Analysis of 465 Normal Adult Human Brains
There was a significant main effect of sex on brain morphology, even after accounting for the larger global volumes of grey and white matter in males. Expand
Navigation-related structural change in the hippocampi of taxi drivers.
Structural MRIs of the brains of humans with extensive navigation experience, licensed London taxi drivers, were analyzed and compared with those of control subjects who did not drive taxis, finding a capacity for local plastic change in the structure of the healthy adult human brain in response to environmental demands. Expand
Somatotopic Representation of Action Words in Human Motor and Premotor Cortex
It is demonstrated that the referential meaning of action words has a correlate in the somatotopic activation of motor and premotor cortex, which rules out a unified "meaning center" in the human brain and supports a dynamic view according to which words are processed by distributed neuronal assemblies with cortical topographies that reflect word semantics. Expand
The problem of functional localization in the human brain
Methods for reporting location in functional imaging are reviewed and the problems that arise from the great variability in brain anatomy between individuals are discussed. Expand
The Processing of Temporal Pitch and Melody Information in Auditory Cortex
The results support the view that there is hierarchy of pitch processing in which the center of activity moves anterolaterally away from primary auditory cortex as the processing of melodic sounds proceeds. Expand
The neural mechanisms of speech comprehension: fMRI studies of semantic ambiguity.
Two functional magnetic resonance studies use the phenomenon of semantic ambiguity to identify regions within the fronto-temporal language network that subserve the semantic aspects of spoken language comprehension. Expand
Lexical information drives perceptual learning of distorted speech: evidence from the comprehension of noise-vocoded sentences.
Perceptual learning of noise-vocoded speech depends on higher level information, consistent with top-down, lexically driven learning, which may facilitate comprehension of speech in an unfamiliar accent or following cochlear implantation. Expand
Spectral and temporal processing in human auditory cortex.
Hierarchical processing suggests that spectrally and temporally complex stimuli will evoke more activation than do simple stimuli, particularly in non-primary auditory fields. This hypothesis wasExpand