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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Research in autophagy continues to accelerate,(1) and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoringExpand
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.
The mitochondrial inner membrane consists of two domains, inner boundary membrane and cristae membrane that are connected by crista junctions. Mitofilin/Fcj1 was reported to be involved in formationExpand
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PEX Genes in Fungal Genomes: Common, Rare or Redundant
PEX genes encode proteins, termed peroxins, that are required for the biogenesis and proliferation of microbodies (peroxisomes). We have screened the available protein and DNA databases to identifyExpand
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Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae
Saccharomyces cerevisiae contains three dynamin-related-proteins, Vps1p, Dnm1p and Mgm1p. Previous data from glucose-grown VPS1 and DNM1 null mutants suggested that Vps1p, but not Dnm1p, plays a roleExpand
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Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1
ABSTRACT Allelic forms of DRG1/AFG2 confer resistance to the drug diazaborine, an inhibitor of ribosome biogenesis in Saccharomyces cerevisiae. Our results show that the AAA-ATPase Drg1 is essentialExpand
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Lipid droplet autophagy in the yeast Saccharomyces cerevisiae
Lipid droplet formation and degradation are pivotal processes in preventing lipotoxicity and providing energy sources and signaling molecules. This is the first demonstration of lipid dropletExpand
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Autophagy: principles and significance in health and disease.
Degradation processes are important for optimal functioning of eukaryotic cells. The two major protein degradation pathways in eukaryotes are the ubiquitin-proteasome pathway and autophagy. ThisExpand
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Uniform nomenclature for the mitochondrial contact site and cristae organizing system
The mitochondrial inner membrane contains a large protein complex that functions in inner membrane organization and formation of membrane contact sites. The complex was variably named theExpand
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Central role of Mic10 in the mitochondrial contact site and cristae organizing system.
The mitochondrial contact site and cristae organizing system (MICOS) is a conserved multi-subunit complex crucial for maintaining the characteristic architecture of mitochondria. Studies withExpand
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