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Enzymatic transformation of platycosides and one-step separation of platycodin D by high-speed countercurrent chromatography.
TLDR
The results strongly support the advantage of enzymatic transformation of the platycosides for the efficient enrichment of platycodin D in the complicated extract of the medicinal plant. Expand
Network analysis of the metabolome and transcriptome reveals novel regulation of potato pigmentation
Highlight An integrated approach of metabolomics and transcriptomics was applied to understand regulatory networks associated with biosynthesis of anthocyanins that are differentially regulated inExpand
Rational development of a selection model for solvent gradients in single-step separation of ginsenosides from Panax ginseng using high-speed counter-current chromatography.
TLDR
A new model of solvent gradients selection was rationally developed for the preparative separation of target compounds and was applied to the one-step separation of eight ginsenosides from Panax ginseng. Expand
Preparative isolation of four ginsenosides from Korean red ginseng (steam-treated Panax ginseng C. A. Meyer), by high-speed counter-current chromatography coupled with evaporative light scattering
TLDR
This study isolated four known ginsenosides Rg3, Rk1, Rg5 and F4 from Korean red ginseng by high-speed counter-current chromatography coupled with evaporative light scattering detection (ELSD), and their structures were characterized by electrospray ionization mass spectrometry (ESI-MS), (1)H NMR and (13)C NMR. Expand
Preparative separation of minor saponins from Platycodi Radix by high-speed counter-current chromatography.
TLDR
The developed method provides the preparative and rapid separation of minor saponins in the crude extract of Platycodi Radix using high-speed counter-current chromatography and preparative reversed-phase high-performance liquid chromatography. Expand
Liquid chromatography/mass spectrometry-based structural analysis of new platycoside metabolites transformed by human intestinal bacteria.
TLDR
The analytical tools presented in this study made it possible to obtain a rapid and complete characterization of new metabolites and their metabolism pathway in human intestinal bacteria. Expand
Dose-Dependent Metabolic Alterations in Human Cells Exposed to Gamma Irradiation
TLDR
The results suggest that MS-based metabolite profiling of γ-radiation-exposed human cells provides insight into the global metabolic alterations in these cells. Expand
Separation of two cytotoxic saponins from the roots of Adenophora triphylla var. japonica by high-speed counter-current chromatography.
TLDR
Two cytotoxic saponins were isolated for the first time from the roots of Adenophora triphylla by high-speed counter-current chromatography (HSCCC). Expand
Metabolite profiling to discriminate different species and genus from thistles in Korea using liquid chromatography with quadrupole time-of-flight mass spectrometry.
TLDR
It is suggested that liquid chromatography with quadrupole time-of-flight mass spectrometry untargeted metabolomic profiling with chemometric analysis is an efficient and powerful tool for discriminating between different species of medicinal herbs. Expand
Identification and metabolite profiling of alkaloids in aerial parts of Papaver rhoeas by liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry
TLDR
The liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry method can be a powerful tool for the identification of diverse metabolites in the genus Papaver and may help understand the biosynthesis of alkaloids in P. rhoeas and evaluate the quality of this plant for possible medicinal applications. Expand
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