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Practical Issues in the Clinical Application of Mismatch Negativity
The mismatch negativity (MMN) recordings provide an objective measure of the preattentive, automatic auditory discrimination function. This article deals with issues central to the recording of theExpand
Early and Late Mismatch Negativity Elicited by Words and Speech-Like Stimuli in Children
In auditory perception the brain's attentional and preattentional mechanisms select certain stimuli for preferential processing and filter out irrelevant input. This study investigated nonattentiveExpand
Seizures in the developing brain: Cellular and molecular mechanisms of neuronal damage, neurogenesis and cellular reorganization
  • I. Holopainen
  • Biology, Medicine
  • Neurochemistry International
  • 1 May 2008
Epilepsy is a common neurological disorder that occurs more frequently in children than in adults. The extent that prolonged seizure activity, i.e. status epilepticus (SE), and repeated, briefExpand
Attenuated auditory event-related potential (mismatch negativity) in children with developmental dysphasia.
An attention-independent negative wave-form termed 'mismatch negativity' (MMN) of the auditory event-related potentials (ERPs) was studied in ten children (3-6 years) with developmental dysphasia andExpand
Kainic acid‐induced status epilepticus alters GABAA receptor subunit mRNA and protein expression in the developing rat hippocampus
Kainic acid‐induced status epilepticus leads to structural and functional changes in inhibitory GABAA receptors in the adult rat hippocampus, but whether similar changes occur in the developing ratExpand
Focal and global cortical hypometabolism in patients with newly diagnosed infantile spasms
Objective To evaluate the occurrence and prognostic importance of focal defects in cerebral cortical glucose metabolism in infants with newly diagnosed symptomatic and cryptogenic infantile spasms.Expand
Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus
BackgroundStatus epilepticus (SE) is proposed to lead to an age-dependent acute activation of a repertoire of inflammatory processes, which may contribute to neuronal damage in the hippocampus. TheExpand
Histamine‐immunoreactive neurons in the mouse and rat suprachiasmatic nucleus
Among the well‐established roles of the neurotransmitter histamine (HA) is that as a regulator of the sleep–wake cycle, which early gained HA a reputation as a ‘waking substance’. TheExpand
Sodium‐dependent high‐affinity uptake of taurine in cultured cerebellar granule cells and astrocytes
Taurine uptake in cultured cerebellar granule cells and astrocytes consisted of a saturable high‐affinity component and nonsaturable diffusion. The transport constant (Km) was significantly lower andExpand
Glutamate receptor agonists increase intracellular Ca2+ independently of voltage-gated Ca2+ channels in rat cerebellar granule cells
Changes in membrane potential and cytosolic free Ca2+ concentrations, [Ca2+]i, in response to L-glutamate and glutamate receptor agonists were measured in rat cerebellar granule cells grown onExpand