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- Publications
- Influence
Ursodeoxycholic acid in the treatment of cholestasis of pregnancy: a randomized, double-blind study controlled with placebo.
BACKGROUND/AIMS
Intense pruritus and the risk of stillbirths and premature deliveries justify the search for an effective pharmacologic treatment of intrahepatic cholestasis of pregnancy. This study… Expand
Selenium, zinc and copper plasma levels in intrahepatic cholestasis of pregnancy, in normal pregnancies and in healthy individuals, in Chile.
BACKGROUND/AIMS
Low blood Se levels have been previously shown in normal pregnancies (third trimester) and significantly lower levels in patients with intrahepatic cholestasis of pregnancy (ICP), in… Expand
Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis.
- Yannick Bacq, L. Sentilhes, +8 authors V. Di Martino
- Medicine
- Gastroenterology
- 1 December 2012
BACKGROUND & AIMS
We performed a meta-analysis to evaluate the effects of ursodeoxycholic acid (UDCA) on pruritus, liver test results, and outcomes of babies born to women with intrahepatic… Expand
Effects of ursodeoxycholic acid in patients with intrahepatic cholestasis of pregnancy
- J. Palma, H. Reyes, +6 authors A. M. Danitz
- Medicine
- Hepatology
- 1 June 1992
The efficacy and safety of ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy was investigated in an open pilot study. Five patients received 1 gm/day of ursodeoxycholic… Expand
Profiles of bile acids and progesterone metabolites in the urine and serum of women with intrahepatic cholestasis of pregnancy.
- L. Meng, H. Reyes, J. Palma, I. Hernández, J. Ribalta, J. Sjövall
- Chemistry, Medicine
- Journal of hepatology
- 1 August 1997
BACKGROUND/AIMS AND METHODS
The etiology of intrahepatic cholestasis of pregnancy (JCP) is unknown. We have performed comprehensive chromatographic and mass spectrometric analyses of progesterone… Expand
Ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy.
- R. Zapata, L. Sandoval, +6 authors Juan Jorge Silva
- Medicine
- Liver international : official journal of the…
- 1 June 2005
Abstract: Objective: To assess the efficacy of ursodeoxycholic acid (UDCA) in patients with intrahepatic cholestasis of pregnancy (ICP) and in the outcome of pregnancy.
Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: Effect of ursodeoxycholic acid therapy
- L. Meng, H. Reyes, +4 authors J. Sjovall
- Medicine
- Hepatology
- 1 December 1997
The concentrations in serum of sulfated metabolites of progesterone are known to be elevated in patients with intrahepatic cholestasis of pregnancy (ICP). The profiles of these metabolites and… Expand
Effects of ursodeoxycholic acid on conjugated bile acids and progesterone metabolites in serum and urine of patients with intrahepatic cholestasis of pregnancy.
- L. Meng, H. Reyes, J. Palma, I. Hernández, J. Ribalta, J. Sjövall
- Chemistry, Medicine
- Journal of hepatology
- 1 December 1997
BACKGROUND/AIMS AND METHODS
The mechanism(s) behind the effects of ursodeoxycholic acid on serum steroid sulphate profiles in patients with intrahepatic cholestasis of pregnancy is not clear.… Expand
Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy.
- M. González, J. Iglesias, +6 authors C. Molina
- Medicine
- Journal of hepatology
- 1992
Is a leaky gut involved in the pathogenesis of intrahepatic cholestasis of pregnancy?
Increased gastrointestinal permeability has been demonstrated in several liver diseases. It may facilitate the absorption of gut‐derived endotoxin‐stimulating Kupffer cells to release proinflammatory… Expand
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