I. Helal

Publications66
h-index14
Citations1,006
Highly Influential Citations46
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Glomerular hyperfiltration: definitions, mechanisms and clinical implications
Glomerular hyperfiltration is a phenomenon that can occur in various clinical conditions including kidney disease. No single definition of glomerular hyperfiltration has been agreed upon, and the… Expand
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High sirolimus levels may induce focal segmental glomerulosclerosis de novo.
Sirolimus has been associated with high-range proteinuria when used in replacement of calcineurin inhibitors in renal transplant recipients with chronic allograft nephropathy (CAN). Primary FSGS was… Expand
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Glomerular hyperfiltration and renal progression in children with autosomal dominant polycystic kidney disease.
BACKGROUND AND OBJECTIVES The purpose of this study was to determine whether glomerular hyperfiltration (GH) occurring early in autosomal dominant polycystic kidney disease (ADPKD) is indicative of… Expand
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Prevalence of Cardiovascular Events in Patients with Autosomal Dominant Polycystic Kidney Disease
Background: This study evaluates the prevalence of cardiovascular events in autosomal dominant polycystic kidney disease (ADPKD) patients. Methods: We distributed surveys to 1,439 subjects from our… Expand
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Changing referral characteristics of patients with autosomal dominant polycystic kidney disease.
OBJECTIVE Autosomal dominant polycystic kidney disease is the most frequent life-threatening hereditary disease. The study objective was to assess whether the clinical characteristics of patients… Expand
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Cardiovascular risk factors in hemodialysis and peritoneal dialysis patients.
Cardiovascular diseases are a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). The aim of our investigation was the evaluation of an extensive cardiovascular… Expand
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The impact of type II diabetes mellitus in patients with autosomal dominant polycystic kidney disease.
BACKGROUND The epidemic of obesity and diabetes is increasing within the USA and worldwide. We have previously shown that body mass index has increased significantly in autosomal dominant polycystic… Expand
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Emergent Early Markers of Renal Progression in Autosomal-Dominant Polycystic Kidney Disease Patients: Implications for Prevention and Treatment
Autosomal-dominant polycystic kidney disease (ADPKD) is the most common single cause of end-stage renal disease after diabetes, hypertension and glomerulonephritis. The clinical course of ADPKD is… Expand
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Serum uric acid, kidney volume and progression in autosomal-dominant polycystic kidney disease.
BACKGROUND Hyperuricemia has been implicated in the development and progression of chronic kidney disease, both in animal experiments and in clinical studies. As a potentially modifiable risk factor,… Expand
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Impact of dialysis modality on posttransplantation results in kidney transplantation.
Studies looking at the type of pretransplantation renal replacement therapy on graft and patient survivals after kidney transplantation have produced conflicting results. Therefore, we studied the… Expand
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