• Publications
  • Influence
Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase.
The lipopeptide antifungal agents, echinocandins, papulacandins, and pneumocandins, kill Candida albicans by inhibiting glucan synthesis. For this fungus, there is a good correlation of in vitroExpand
  • 300
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Variant mitoses in lower eukaryotes: indicators of the evolution of mitosis.
  • I. Heath
  • Biology, Medicine
  • International review of cytology
  • 1980
Publisher Summary Mitosis is defined as all those types of nuclear division that produce two, or rarely more, daughter nuclei, each containing a chromosome complement approximately similar to that ofExpand
  • 304
  • 13
The Roles of Actin in Tip Growth of Fungi
Publisher Summary This chapter discusses the multiple features of tip growth and examines the organization of actin in the growth zones. A synthesis of these data provides models for the possibleExpand
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An atlas of fungal ultrastructure
  • 107
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A unified hypothesis for the role of membrane bound enzyme complexes and microtubules in plant cell wall synthesis.
  • I. Heath
  • Biology, Medicine
  • Journal of theoretical biology
  • 1974
In an attempt to provide a unified hypothesis to account for the various aspects of oriented cellulose fibril synthesis it is proposed that plasmalemma located cellulose synthetase enzyme complexesExpand
  • 196
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Roles of calcium ions in hyphal tip growth.
A role for Ca2+ in the tip growth process of fungal hyphae and other eukaryotic walled cells has been widely explored, following the earlier indications of their importance by Jaffe, Steer, and theirExpand
  • 245
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  • PDF
Plasma membrane-adjacent actin filaments, but not microtubules, are essential for both polarization and hyphal tip morphogenesis in Saprolegnia ferax and Neurospora crassa.
The organization and roles of F-actin and microtubules in the maintenance and initiation of hyphal tip growth have been analyzed in Saprolegnia ferax and Neurospora crassa. In hyphae of both species,Expand
  • 76
  • 7
The Cytoskeleton in Hyphal Growth, Organelle Movements, and Mitosis
The cytoskeleton is an integrated and coordinated meshwork of filamentous polymers which are interconnected and linked to other cellular structures by a diverse array of molecules. This meshworkExpand
  • 68
  • 7
Radial F-actin arrays precede new hypha formation in Saprolegnia: implications for establishing polar growth and regulating tip morphogenesis.
The roles of cortical F-actin in initiating and regulating polarized cell expansion in the form of hyphal tip morphogenesis were investigated by analyzing long term effects of F-actin disruption byExpand
  • 69
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  • PDF
Mechanisms of hyphal tip growth: tube dwelling amebae revisited.
Over 100 years ago, Reinhardt suggested that hyphal tip growth is comparable to ameboid movement inside a tube; the apical cytoplasm being protruded like a pseudopodium with the wall assembled on itsExpand
  • 69
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