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CCN5/WISP-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells.
The systematic investigation of the CCN5 expression profile in noninvasive and invasive breast tumor samples and its functional relevance in breast cancer progression suggests that the protective effect ofCCN5 in Breast cancer progression may have important therapeutic implications. Expand
Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis
It is demonstrated that cyr61/CCN1 silencing in Panc-1-SP cells reverses the stemness features and tumor initiating potency of these cells, implying a miRNA-based mechanism for the regulation of aggressive behaviors of pancreatic cancer cells by Cyr61/ CCN1. Expand
Characterization of acrylamide polymers for enhanced oil recovery
Four different copolymers, of acrylamide and acrylic acid, acrylamide and 2-acrylamido-2-methyl propane sulfonic acid, N,N-dimethylacrylamide and acrylic acid, and N,N-dimethylacrylamide andExpand
Intraspecific Variation in Commiphora wightii Populations Based on Internal Transcribed Spacer (ITS1-5.8S-ITS2) Sequences of rDNA
Analysis of nucleotide sequences of the internal transcribed spacer of rDNAs revealed low genetic diversity and high population structure of C. wightii, and Mantel’s test showed a statistically significant positive correlation between genetic and geographic distance. Expand
Emblica officinalis Extract Induces Autophagy and Inhibits Human Ovarian Cancer Cell Proliferation, Angiogenesis, Growth of Mouse Xenograft Tumors
It is determined that Amla extract (AE) has anti-proliferative effects on OC cells under both in vitro and in vivo conditions, and may prove useful as an alternative or adjunct therapeutic approach in helping to fight OC. Expand
Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1
New insights into the roles of tumor cell-secreted PDGF-B-NRP-1 signaling in MSCs-fate determination may help to develop new antiangiogenic strategies to prevent the tumor growth and metastasis and result in more effective cancer therapies. Expand
A Second-Generation 2-Methoxyestradiol Prodrug Is Effective against Barrett's Adenocarcinoma in a Mouse Xenograft Model
This double prodrug of 2-ME2 is effective as an antiproliferative and anticancer agent for both in vitro and in vivo studies against Barrett esophageal adenocarcinoma (BEAC) and provided greater potency than 2- ME2 in inhibiting the growth of BEAC xenografts. Expand
Oxidation of high sulphur coal. Part 2. Desulphurisation of organic sulphur by hydrogen peroxide in presence of metal ions
Abstract This paper describes a simple oxidative method of desulphurisation of coal organic sulphur carried out by using hydrogen peroxide as an oxidant. Desulphurisation achieved up to the extent ofExpand
Population genetic structure of the endangered and endemic medicinal plant Commiphorawightii
Random amplified polymorphic DNA analysis was conducted to find the genetic variation among 7 populations of Commiphora wightii and revealed a highly significant positive correlation between genetic and geographic distance. Expand
Pancreatic Tumor Cell Secreted CCN1/Cyr61 Promotes Endothelial cell migration and Aberrant Neovascularization
In vitro and in vivo models show that pancreatic cancer cell generated unique microenvironments can underlie endothelial cell migration and tumor angiogenesis, and a novel CCN1 signaling program is identified which activates Sonic Hedgehog (SHh) through autocrine-paracrine circuits to promote endothelium cell Migration and tumorAngiogenesis. Expand