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NEONATAL EXPOSURE TO DI(N-BUTYL) PHTHALATE (DBP) ALTERS MALE REPRODUCTIVE-TRACT DEVELOPMENT
  • H. Kim, T. Kim, +5 authors S. Han
  • Biology, Medicine
  • Journal of toxicology and environmental health…
  • 1 December 2004
The purpose of this study was to evaluate male reproductive-organ development in early postnatal male rats following neonatal exposure to di(n-butyl) phthalate (DBP) and identify a mechanism ofExpand
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Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide.
  • H. Kim, Jae-Ho Shin, +6 authors S. Han
  • Chemistry, Medicine
  • Toxicological sciences : an official journal of…
  • 1 May 2002
The Endocrine Disrupter Screening and Testing Advisory Committee (EDSTAC) has recommended the rodent pubertal female assay as a Tier I test to detect potential endocrine disrupters (EDs). This assayExpand
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Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays.
Pyrethroid insecticides are among the most commonly used classes of insecticides worldwide, but their endocrine disrupting activities remain unclear. Therefore, in the present study, we examined theExpand
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Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209.
  • E. Lee, T. Kim, +13 authors H. Kim
  • Chemistry, Medicine
  • The Journal of toxicological sciences
  • 1 August 2010
Our goal in the present study was to evaluate whether decabromodiphenyl ether (BDE-209), which is the most abundant polybrominated diphenyl ether (PBDE) found in human samples, affects against targetExpand
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Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay.
The rodent Hershberger assay proposed by the Organization for Economic Co-operation and Development (OECD) is in the process of the validating a test method to detecting the androgenic orExpand
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Effects of in Utero Exposure to DI(n-Butyl) Phthalate on Development of Male Reproductive Tracts in Sprague-Dawley Rats
  • T. Kim, K. K. Jung, +10 authors T. Kang
  • Biology, Medicine
  • Journal of toxicology and environmental health…
  • 13 October 2010
The purpose of this study was to determine the effects of di(n-butyl) phthalate (DBP) administration on male reproductive organ development in F1 Sprague-Dawley rats following in utero exposure.Expand
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Comparative estrogenic effects of p-nonylphenol by 3-day uterotrophic assay and female pubertal onset assay.
Nonylphenol (NP) is widely used as a component of detergents, paints, pesticides, and many other formulated products. Several studies have demonstrated that NP is estrogenic in fish, avian, andExpand
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EFFECTS OF FLUTAMIDE ON PUBERTY IN MALE RATS: AN EVALUATION OF THE PROTOCOL FOR THE ASSESSMENT OF PUBERTAL DEVELOPMENT AND THYROID FUNCTION
To establish a test protocol for the rodent 20-d thyroid/pubertal assay, flutamide, a nonsteroidal androgen antagonist, was administered to intact male Sprague-Dawley rats from postnatal d 33 for 20Expand
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Evaluation of in vitro screening system for estrogenicity: comparison of stably transfected human estrogen receptor-α transcriptional activation (OECD TG455) assay and estrogen receptor (ER) binding
The estrogenic activity of industrial chemicals, di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), benzylbutyl phthalate (BBP), diethyl phthalate (DEP), tetrabromobisphenol A (TBBPA),Expand
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Gestational exposure to nonylphenol causes precocious mammary gland development in female rat offspring.
This study examined whether or not exposure to 4-nonylphenol (NP) during late gestation affects reproductive and mammary development in the offspring of female rats. Time pregnant Long Evans ratsExpand
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