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Population genomics of domestic and wild yeasts
Since the completion of the genome sequence of Saccharomyces cerevisiae in 1996 (refs 1, 2), there has been a large increase in complete genome sequences, accompanied by great advances in ourExpand
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The Genome of the African Trypanosome Trypanosoma brucei
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11 megabase-sized chromosomes of TrypanosomaExpand
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The genome of the social amoeba Dictyostelium discoideum
The social amoebae are exceptional in their ability to alternate between unicellular and multicellular forms. Here we describe the genome of the best-studied member of this group, DictyosteliumExpand
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Population genomics of domestic and wild yeasts
The natural genetics of an organism is determined by the distribution of sequences of its genome. Here we present one- to four-fold, with some deeper, coverage of the genome sequences of over seventyExpand
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Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution
Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and that many functional properties of transcripts are based not onExpand
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The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
Bacterial infections of the lungs of cystic fibrosis (CF) patients cause major complications in the treatment of this common genetic disease. Burkholderia cenocepacia infection is particularlyExpand
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Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
Human cancers often carry many somatically acquired genomic rearrangements, some of which may be implicated in cancer development. However, conventional strategies for characterizing rearrangementsExpand
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Telomeric Expression Sites Are Highly Conserved in Trypanosoma brucei
Subtelomeric regions are often under-represented in genome sequences of eukaryotes. One of the best known examples of the use of telomere proximity for adaptive purposes are the bloodstreamExpand
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High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi
Isolates of Salmonella enterica serovar Typhi (Typhi), a human-restricted bacterial pathogen that causes typhoid, show limited genetic variation. We generated whole-genome sequences for 19 TyphiExpand
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Insights into hominid evolution from the gorilla genome sequence
Gorillas are humans’ closest living relatives after chimpanzees, and are of comparable importance for the study of human origins and evolution. Here we present the assembly and analysis of a genomeExpand
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